Lattice light sheet microscopy reveals 4D force propagation dynamics and leading-edge behaviors in an embryonic epithelium in Drosophila

TE Vanderleest, Y Xie, R Budhathoki, K Linvill… - Current Biology, 2024 - cell.com
How pulsed contractile dynamics drive the remodeling of cell and tissue topologies in
epithelial sheets has been a key question in development and disease. Due to constraints in …

A Rab39-Klp98A-Rab35 endocytic recycling pathway is essential for rapid Golgi-dependent furrow ingression

H Miao, M Millage, KR Rollins… - Development, 2023 - journals.biologists.com
Ingression of the plasma membrane is an essential part of the cell topology-distorting
repertoire and a key element in animal cell cytokinesis. Many embryos have rapid cleavage …

β-H-Spectrin is a key component of an apical-medial hub of proteins during cell wedging in tube morphogenesis

G Gillard, K Röper - Journal of Cell Science, 2024 - journals.biologists.com
Coordinated cell shape changes are a major driver of tissue morphogenesis, with apical
constriction of epithelial cells leading to tissue bending. We previously identified that …

Interface extension is a continuum property suggesting a linkage between AP contractile and DV lengthening processes

TE Vanderleest, Y Xie, C Smits… - Molecular Biology of …, 2022 - Am Soc Cell Biol
In the early Drosophila embryo, the elongation of the anterior-posterior (AP) body axis is
driven by cell intercalation in the germband epithelium. Neighboring cells intercalate …

[HTML][HTML] A Highlights from MBoC Selection: Interface extension is a continuum property suggesting a linkage between AP contractile and DV lengthening processes

TE Vanderleest, Y Xie, C Smits… - Molecular Biology of …, 2022 - ncbi.nlm.nih.gov
In the early Drosophila embryo, the elongation of the anterior-posterior (AP) body axis is
driven by cell intercalation in the germband epithelium. Neighboring cells intercalate …

Intercalate or invaginate: PI (3, 4, 5) P3 governs a membrane constriction switch in cell shaping

G Baonza, G Herranz, F Martin-Belmonte - Developmental Cell, 2021 - cell.com
Although contractile processes, from tissue invagination to cell intercalation, utilize diverse
ratcheting mechanisms, little is known about how ratcheting becomes engaged at specific …