Clozapine haematological monitoring for neutropenia: a global perspective

E Oloyede, G Blackman, E Whiskey… - Epidemiology and …, 2022 - cambridge.org
AimsClozapine is licensed for treatment-resistant psychosis and remains underutilised. This
may berelated to the stringent haematological monitoring requirements that are mandatory …

[PDF][PDF] Reflections on the complex history of the concept of clozapine-induced inflammation during titration

J de Leon - Psychiatria Danubina, 2022 - hrcak.srce.hr
REFLECTIONS ON THE COMPLEX HISTORY OF THE CONCEPT OF CLOZAPINE-INDUCED
INFLAMMATION DURING TITRATION Page 1 411 Psychiatria Danubina, 2022; Vol. 34, No. 3 …

Risks and benefits of clozapine and lithium co-prescribing: a systematic review and expert recommendations

H Verdoux, C Quiles, J de Leon - Schizophrenia research, 2023 - Elsevier
Objectives To identify the risks and benefits of clozapine‑lithium co-prescription. Methods
Articles published in English or French were identified with a MEDLINE, Web of Sciences …

[HTML][HTML] Revealing the reporting disparity: VigiBase highlights underreporting of clozapine in other Western European countries compared to the UK

C De las Cuevas, EJ Sanz, JA Gross, CU Correll… - Schizophrenia …, 2024 - Elsevier
Background Pharmacovigilance studies indicate clozapine history is marked by adverse
drug reactions (ADRs). Objective In a 2021 article, the United Kingdom (UK) had> 90% of …

Clozapine optimization: a delphi consensus guideline from the treatment response and resistance in psychosis working group

E Wagner, D Siskind, P Falkai, O Howes… - Schizophrenia …, 2023 - academic.oup.com
Abstract Background and Hypothesis There is limited evidence to guide the approaches to
clozapine treatment. Accordingly, an international initiative was undertaken with the aim of …

Association between initial clozapine titration and pneumonia risk among patients with schizophrenia in a Korean tertiary hospital

N Kang, SH Kim, J Kim, S Kim, J Jang, H Yoon… - Schizophrenia …, 2024 - Elsevier
Pneumonia is a significant adverse drug reaction (ADR) associated with clozapine,
characterized by high mortality and potential linkage with other inflammatory responses …

[HTML][HTML] Clozapine-associated pericarditis and pancreatitis in children and adolescents: A systematic literature review and pharmacovigilance study using the …

R de Filippis, C De las Cuevas, EJ Sanz… - Schizophrenia …, 2024 - Elsevier
Background The literature has paid very little attention to pericarditis, pericardial effusion
and pancreatitis during clozapine treatment in children and adolescents. Methods Cases of …

Screening the European pharmacovigilance database for reports of clozapine-related DRESS syndrome: 47 novel cases

R de Filippis, JM Kane, N Kuzo, E Spina… - European …, 2022 - Elsevier
Clozapine-related drug reaction with eosinophilia and systemic symptoms (DRESS)
syndrome is a rare adverse reaction. We aimed to screen a large pharmacovigilance …

[PDF][PDF] Four cases of myocarditis in US hospitals possibly associated with clozapine poor metabolism and a comparison with prior published cases

M Koenig, B McCollum, JK Spivey… - …, 2022 - epa.niif.hu
Objectives: Clozapine-induced myocarditis may be a hypersensitivity reaction due to titration
that was too rapid for a patient's clozapine metabolism. Obesity, infections, and inhibitors …

Immunomodulatory effects of clozapine: More than just a side effect in schizophrenia

A Amerio, L Magnani, G Arduino, F Fesce… - Current …, 2024 - benthamdirect.com
Recent evidence suggests a possible relationship between the immune system and
schizophrenia spectrum disorders (SSDs), as neuroinflammation appears to play a role in …