Breast cancer is one of the most frequently diagnosed cancers that is threatening women's
life. Current clinical treatment regimens for breast cancer often involve neoadjuvant and …

In the drug delivery system, the transdermal drug delivery system has the advantages of
painless administration, avoiding the first-pass metabolism, sustained therapeutic effect, and …

Chemotherapeutic cytotoxic agents such as paclitaxel (PTX) are considered essential for the
treatment of various cancers. However, PTX injection is associated with severe systemic …

In present investigation, we developed paclitaxel (PTX)-loaded adenosine (ADN)-
conjugated PLGA nanoparticles for combating triple-negative breast cancer (TNBC), where …

Ferroptosis is a non-apoptotic cell death pathway characterized by the accumulation of lipid-
peroxy radicals within the affected cells. Here, we investigate the synergistic capacity of …

Triple-negative breast cancer (TNBC) belongs to the category of the most destructive forms
of breast cancer. Being a highly potent chemotherapeutic agent, paclitaxel (PTX) is …

Breast cancer is the second highest cause of cancer-related mortality in women worldwide
and in the United States, accounting for around 571,000 deaths per year. Early detection of …

Gellan gum (GG) has attracted considerable attention as a versatile biopolymer with
numerous potential biological applications, especially in the fields of tissue engineering …

Resveratrol (RVT) is a polyphenolic phytoestrogen which has shown antiproliferative activity
in breast cancer. However, its low bioavailability and short half-life have restricted its use …

Exemestane (EXE) a potent third generation aromatase inhibitor and is employed as first
line treatment in estrogen receptor positive breast cancer. Its oral bioavailability is only 5 …