Mechanisms of apoptosis modulation by curcumin: Implications for cancer therapy

K Mortezaee, E Salehi… - Journal of cellular …, 2019 - Wiley Online Library
Cancer incidences are growing and cause millions of deaths worldwide. Cancer therapy is
one of the most important challenges in medicine. Improving therapeutic outcomes from …

Radiation‐induced normal tissue damage: oxidative stress and epigenetic mechanisms

J Wei, B Wang, H Wang, L Meng… - Oxidative medicine …, 2019 - Wiley Online Library
Radiotherapy (RT) is currently one of the leading treatments for various cancers; however, it
may cause damage to healthy tissue, with both short‐term and long‐term side effects …

Abscopal effect in radioimmunotherapy

M Ashrafizadeh, B Farhood, AE Musa, S Taeb… - International …, 2020 - Elsevier
Abscopal effect is an interesting phenomenon in radiobiology that causes activation of
immune system against cancer cells. Traditionally, this phenomenon was known as a …

Mechanisms and significance of therapy-induced and spontaneous senescence of cancer cells

J Mikuła-Pietrasik, A Niklas, P Uruski, A Tykarski… - Cellular and Molecular …, 2020 - Springer
In contrast to the well-recognized replicative and stress-induced premature senescence of
normal somatic cells, mechanisms and clinical implications of senescence of cancer cells …

The effects of ionising and non-ionising electromagnetic radiation on extracellular matrix proteins

RJ Tuieng, SH Cartmell, CC Kirwan, MJ Sherratt - Cells, 2021 - mdpi.com
Exposure to sub-lethal doses of ionising and non-ionising electromagnetic radiation can
impact human health and well-being as a consequence of, for example, the side effects of …

[HTML][HTML] Apelin+ endothelial niche cells control hematopoiesis and mediate vascular regeneration after myeloablative injury

Q Chen, Y Liu, HW Jeong, M Stehling, B Zhou… - Cell stem cell, 2019 - cell.com
Radiotherapy and chemotherapy disrupt bone vasculature, but the underlying causes and
mechanisms enabling vessel regeneration after bone marrow (BM) transplantation remain …

Sulforaphane-mediated Nrf2 activation prevents radiation-induced skin injury through inhibiting the oxidative-stress-activated DNA damage and NLRP3 …

J Wei, Q Zhao, Y Zhang, W Shi, H Wang, Z Zheng… - Antioxidants, 2021 - mdpi.com
This article mainly observed the protective effect of sulforaphane (SFN) on radiation-induced
skin injury (RISI). In addition, we will discuss the mechanism of SFN's protection on RISI. The …

Radiation protection and mitigation by natural antioxidants and flavonoids: implications to radiotherapy and radiation disasters

R Yahyapour, D Shabeeb, M Cheki… - Current molecular …, 2018 - ingentaconnect.com
Background: Nowadays, ionizing radiations are used for various medical and terroristic
aims. These purposes involve exposure to ionizing radiations. Hence, people are at risk for …

Sulforaphane regulates Nrf2-mediated antioxidant activity and downregulates TGF-β1/Smad pathways to prevent radiation-induced muscle fibrosis

H Wang, B Wang, J Wei, Z Zheng, J Su, C Bian, Y Xin… - Life sciences, 2022 - Elsevier
Aims This study aimed to examine the efficacy of sulforaphane (SFN) in preventing radiation-
induced muscle fibrosis (RIMF) and the potential role in nuclear factor erythroid 2-related …

NADPH oxidase as a target for modulation of radiation response; implications to carcinogenesis and radiotherapy

K Mortezaee, NH Goradel, P Amini… - Current molecular …, 2019 - ingentaconnect.com
Background: Radiotherapy is a treatment modality for cancer. For better therapeutic
efficiency, it could be used in combination with surgery, chemotherapy or immunotherapy. In …