Surface modification for improving immunoassay sensitivity

X Zhou, B Zheng - Lab on a Chip, 2023 - pubs.rsc.org
Immunoassays are widely performed in many fields such as biomarker discovery,
proteomics, drug development, and clinical diagnosis. There is a growing need for high …

Nanofluidic Lab‐On‐A‐Chip Systems for Biosensing in Healthcare

SW Chong, Y Shen, S Palomba, D Vigolo - Small, 2025 - Wiley Online Library
Biosensing plays a vital role in healthcare monitoring, disease detection, and treatment
planning. In recent years, nanofluidic technology has been increasingly explored to be …

Polymer brushes on silica nanostructures prepared by aminopropylsilatrane click chemistry: superior antifouling and biofunctionality

J Andersson, J Järlebark, S Kk… - … Applied Materials & …, 2023 - ACS Publications
In nanobiotechnology, the importance of controlling interactions between biological
molecules and surfaces is paramount. In recent years, many devices based on …

Tuning of Surface Charge of Functionalized Poly (Carboxybetaine) Brushes Can Significantly Improve Label‐Free Biosensing in Complex Media

I Víšová, M Houska, M Spasovová… - Advanced Materials …, 2022 - Wiley Online Library
Poly (carboxybetaine) brushes are excellent antifouling platforms allowing facile
functionalization with biorecognition elements via carbodiimide/N‐hydroxysuccinimide …

Probing charge transfer through antifouling polymer brushes by electrochemical methods: The impact of supporting self-assembled monolayer chain length

J Anthi, E Vaněčková, M Spasovová, M Houska… - Analytica Chimica …, 2023 - Elsevier
Ultrathin surface-tethered polymer brushes represent attractive platforms for a wide range of
sensing applications in strategically vital areas such as medicine, forensics, or security. The …

Piezoelectric biosensor with dissipation monitoring enables the analysis of bacterial lytic agent activity

R Obořilová, E Kučerová, T Botka… - Scientific Reports, 2025 - nature.com
Antibiotic-resistant strains of Staphylococcus aureus pose a significant threat in healthcare,
demanding urgent therapeutic solutions. Combining bacteriophages with conventional …

Long-term stability of antifouling poly (carboxybetaine acrylamide) brush coatings

M Vrabcová, M Spasovová, M Houska… - Progress in Organic …, 2024 - Elsevier
A comprehensive understanding how storage conditions affect functional surface properties
of antifouling organic coatings remains a persistent challenge across industry and research …

Optical fibre long-period grating sensors modified with antifouling bio-functional nano-brushes

M Vrabcová, M Spasovová, M Forinová… - Biomaterials …, 2025 - pubs.rsc.org
Recent advances in optical sensing technologies underpin the development of high-
performance, surface-sensitive analytical tools capable of reliable and precise detection of …

[HTML][HTML] Surface Plasmon Resonance Biosensor with Anti-Crossing Modulation Readout

R Hasler, DC Mor, G Aktug, S Fossati, A Tamayo… - Sensors and Actuators B …, 2024 - Elsevier
A novel approach to surface plasmon resonance (SPR) biosensors providing simplified
label-free monitoring of biomolecular affinity binding events is reported. It is based on the …

Effects of storage on stability and performance of carboxybetaine-based polymer brushes

M Vrabcová, M Houska, M Spasovová… - Optical Sensing and …, 2024 - spiedigitallibrary.org
Zwitterionic poly (carboxybetaine) brushes have emerged as promising surface functional
coatings for antifouling labelfree biosensing in complex biological fluids. This study …