An analysis of genetic heterogeneity in untreated cancers

JG Reiter, M Baretti, JM Gerold… - Nature Reviews …, 2019 - nature.com
Genetic intratumoural heterogeneity is a natural consequence of imperfect DNA replication.
Any two randomly selected cells, whether normal or cancerous, are therefore genetically …

Pulmonary sclerosing pneumocytoma: clinical features and prognosis

Q Zheng, J Zhou, G Li, S Man, Z Lin, T Wang… - World Journal of …, 2022 - Springer
Background Pulmonary sclerosing pneumocytoma is a kind of rare benign pulmonary tumor
with potential malignancy. The clinical features, risk factors for prognosis, and optimal …

Salivary mucinous adenocarcinoma is a histologically diverse single entity with recurrent AKT1 E17K mutations: clinicopathologic and molecular characterization with …

LM Rooper, PP Argyris, LDR Thompson… - The American Journal …, 2021 - journals.lww.com
Mucin-producing salivary adenocarcinomas were historically divided into separate colloid
carcinoma, papillary cystadenocarcinoma, and signet ring cell carcinoma diagnoses based …

AKT1 mutations in peripheral bronchiolar papilloma: glandular papilloma and mixed squamous cell and glandular papilloma is distinct from bronchiolar adenoma

E Sasaki, K Masago, S Fujita, A Iwakoshi… - The American Journal …, 2021 - journals.lww.com
Glandular papilloma (GP) and mixed squamous cell and glandular papilloma (MP) are rare
benign pulmonary tumors occurring in the bronchi. Bronchiolar adenoma (BA) was recently …

[HTML][HTML] KRAS mutations drive adenomatoid odontogenic tumor and are independent of clinicopathological features

BP Coura, VF Bernardes, SF De Sousa, JA França… - Modern Pathology, 2019 - Elsevier
Adenomatoid odontogenic tumor is a benign encapsulated epithelial odontogenic tumor that
shows an indolent clinical behavior. We have reported in a few adenomatoid odontogenic …

Risk Stratification Using a Novel Genetic Classifier Including PLEKHS1 Promoter Mutations for Differentiated Thyroid Cancer with Distant Metastasis

CK Jung, SH Jung, S Jeon, YM Jeong, Y Kim, S Lee… - Thyroid, 2020 - liebertpub.com
Background: Although most differentiated thyroid carcinomas (DTCs) have indolent
behavior, DTCs with distant metastasis have a poor prognosis. However, there are no …

[HTML][HTML] Systematic discovery of mutation-directed neo-protein-protein interactions in cancer

X Mo, Q Niu, AA Ivanov, YH Tsang, C Tang, C Shu, Q Li… - Cell, 2022 - cell.com
Comprehensive sequencing of patient tumors reveals genomic mutations across tumor
types that enable tumorigenesis and progression. A subset of oncogenic driver mutations …

[HTML][HTML] AKT1 internal tandem duplications and point mutations are the genetic hallmarks of sclerosing pneumocytoma

YC Yeh, HL Ho, YC Wu, CC Pan, YC Wang, TY Chou - Modern Pathology, 2020 - Elsevier
Sclerosing pneumocytoma is a unique benign neoplasm of the lungs. The molecular
alterations in sclerosing pneumocytoma are not well understood. In a previous whole-exome …

What's new in benign lung tumours?

JM Boland - Histopathology, 2024 - Wiley Online Library
While lung cancer is one of the most common malignancies routinely encountered by
pathologists, benign pulmonary neoplasms are quite rare. However, it is important for …

Recurrent driver mutations in benign tumors

CC Gomes - Mutation Research/Reviews in Mutation Research, 2022 - Elsevier
The understanding of the molecular pathogenesis of benign tumors may bring essential
information to clarify the process of tumorigenesis, and ultimately improve the understanding …