Fungi must meet four criteria to infect humans: growth at human body temperatures, circumvention or penetration of surface barriers, lysis and absorption of tissue, and …
Systemic candidiasis is a common, high-mortality, nosocomial fungal infection. Unexpectedly, it has emerged as a complication of anti-complement C5-targeted …
C Baldin, AS Ibrahim - PLoS pathogens, 2017 - journals.plos.org
During the past 2 decades, mucormycosis has become the third most common invasive fungal infection in patients with hematological malignancies and organ transplantations [1] …
Advances in transcriptome sequencing allow for simultaneous interrogation of differentially expressed genes from multiple species originating from a single RNA sample, termed dual …
Unlike other forms of candidiasis, vulvovaginal candidiasis, caused primarily by the fungal pathogen Candida albicans, is a disease of immunocompetent and otherwise healthy …
Highlights•Candidalysin is the first peptide toxin identified in any human fungal pathogen.•Epithelial cells identify invasive C. albicans by detecting Candidalysin …
Shotgun metatranscriptomics (MTX) is an increasingly practical way to survey microbial community gene function and regulation at scale. This review begins by summarizing the …
Vaginal candidiasis is an extremely common disease predominantly caused by four phylogenetically diverse species: Candida albicans; Candida glabrata; Candida …
HR Conti, VM Bruno, EE Childs, S Daugherty… - Cell host & …, 2016 - cell.com
Signaling through the IL-17 receptor (IL-17R) is required to prevent oropharyngeal candidiasis (OPC) in mice and humans. However, the IL-17-responsive cell type (s) that …