Nanostructured lipid carriers for improved delivery of therapeutics via the oral route
Drug delivery via the oral route has always been challenging for poorly soluble drugs. Acid‐
induced hydrolysis, enzymatic degradation, and poor mucosal absorbency remain the …
induced hydrolysis, enzymatic degradation, and poor mucosal absorbency remain the …
Statistically optimized tacrolimus and thymoquinone co-loaded nanostructured lipid carriers gel for improved topical treatment of psoriasis
The aim of this investigation was to develop and analyze a tacrolimus and thymoquinone co-
loaded nanostructured lipid carriers (TAC-THQ-NLCs)-based nanogel as a new …
loaded nanostructured lipid carriers (TAC-THQ-NLCs)-based nanogel as a new …
Preparation, characterization and in vitro cytotoxicity of Fenofibrate and Nabumetone loaded solid lipid nanoparticles
There is an increasing attention on solid lipid nanoparticles (SLNs) due to their high
biocompatibility and ability to enhance bioavailability for poorly water-soluble drugs …
biocompatibility and ability to enhance bioavailability for poorly water-soluble drugs …
Impact of liquid lipid on development and stability of trimyristin nanostructured lipid carriers for oral delivery of resveratrol
C Houacine, D Adams, KK Singh - Journal of Molecular Liquids, 2020 - Elsevier
Nanostructured lipid carriers (NLCs) have emerged as versatile carriers to improve oral
bioavailability of poorly water-soluble drugs as well as to protect labile drugs from …
bioavailability of poorly water-soluble drugs as well as to protect labile drugs from …
Lipid-nanopotentiated combinatorial delivery of tamoxifen and sulforaphane: ex vivo, in vivo and toxicity studies
Aim: This study aims to load tamoxifen (TAM) and sulforaphane (SFN) into nanostructured
lipid carriers (NLCs) to enhance their oral delivery. Materials & methods: TAM-SFN-NLCs …
lipid carriers (NLCs) to enhance their oral delivery. Materials & methods: TAM-SFN-NLCs …
Design and development of letrozole nanoemulsion: A comparative evaluation of brain targeted nanoemulsion with free letrozole against status epilepticus and …
The target of the current study is to formulate letrozole loaded nanoemulsion (LET-NE) for
the direct nose to brain delivery to reduce peripheral effects of letrozole (LET). LET-NE is …
the direct nose to brain delivery to reduce peripheral effects of letrozole (LET). LET-NE is …
[HTML][HTML] Ultrasonically tailored, chemically engineered and “QbD” enabled fabrication of agomelatine nanoemulsion; optimization, characterization, ex-vivo …
The objective of present study was to develop a nanoemulsion formulation of agomelatine
(BCS class II drug) for the solubility enhancement. Capmul MCM, Tween 80 and PEG-400 …
(BCS class II drug) for the solubility enhancement. Capmul MCM, Tween 80 and PEG-400 …
Risk assessment integrated QbD approach for development of optimized bicontinuous mucoadhesive limicubes for oral delivery of rosuvastatin
Statins are widely prescribed for hyperlipidemia, cancer, and Alzheimer's disease but are
facing some inherent challenges such as low solubility and drug loading, higher hepatic …
facing some inherent challenges such as low solubility and drug loading, higher hepatic …
Nanostructured lipid carrier to overcome stratum corneum barrier for the delivery of agomelatine in rat brain; formula optimization, characterization and brain …
The current work attempted to achieve bypassed hepatic metabolism, controlled release,
and boosted brain distribution of agomelatine by loading in NLC and administering via …
and boosted brain distribution of agomelatine by loading in NLC and administering via …
Design of lipid-based nanocarrier for drug delivery has a double therapy for six common pathogens eradication
Nanostructured lipid-based carriers (NLCs) efficiently improved as potential targeted drug
delivery for six common pathogens eradication. Transmission electron microscopy (TEM) …
delivery for six common pathogens eradication. Transmission electron microscopy (TEM) …