Ambient ionization mass spectrometry: recent developments and applications

CL Feider, A Krieger, RJ DeHoog… - Analytical chemistry, 2019 - ACS Publications
The early 2000s brought a new age in the field of mass spectrometry (MS) with the
introduction of ambient ionization MS techniques. As defined by one of its early visionaries …

Protein analysis by shotgun/bottom-up proteomics

Y Zhang, BR Fonslow, B Shan, MC Baek… - Chemical …, 2013 - ACS Publications
According to Genome Sequencing Project statistics (http://www. ncbi. nlm. nih.
gov/genomes/static/gpstat. html), as of February 16, 2012, complete gene sequences have …

Recent developments in liquid chromatography–mass spectrometry and related techniques

M Holčapek, R Jirásko, M Lísa - Journal of Chromatography A, 2012 - Elsevier
This review summarizes the state-of-art in liquid chromatography–mass spectrometry (LC–
MS) and related techniques with the main focus on recent developments in the last decade …

What protein charging (and supercharging) reveal about the mechanism of electrospray ionization

RR Ogorzalek Loo, R Lakshmanan… - Journal of the American …, 2014 - ACS Publications
Understanding the charging mechanism of electrospray ionization is central to overcoming
shortcomings such as ion suppression or limited dynamic range, and explaining …

A mechanism for ionization of nonvolatile compounds in mass spectrometry: considerations from MALDI and inlet ionization

S Trimpin, B Wang, ED Inutan, J Li… - Journal of The …, 2012 - ACS Publications
Mechanistic arguments relative to matrix-assisted laser desorption/ionization (MALDI) mass
spectrometry (MS) address observations that predominately singly charged ions are …

Zero volt paper spray ionization and its mechanism

M Wleklinski, Y Li, S Bag, D Sarkar… - Analytical …, 2015 - ACS Publications
The analytical performance and a suggested mechanism for zero volt paper spray using
chromatography paper are presented. A spray is generated by the action of the pneumatic …

Recent advances in mass spectrometry techniques for atmospheric chemistry research on molecular‐level

W Zhang, L Xu, H Zhang - Mass Spectrometry Reviews, 2024 - Wiley Online Library
The Earth's atmosphere is composed of an enormous variety of chemical species associated
with trace gases and aerosol particles whose composition and chemistry have critical …

Matrix assisted ionization: new aromatic and nonaromatic matrix compounds producing multiply charged lipid, peptide, and protein ions in the positive and negative …

J Li, ED Inutan, B Wang, CB Lietz… - Journal of the …, 2012 - ACS Publications
Matrix assisted inlet ionization (MAII) is a method in which a matrix: analyte mixture
produces mass spectra nearly identical to electrospray ionization without the application of a …

A tutorial: Laserspray ionization and related laser‐based ionization methods for use in mass spectrometry

S Trimpin - Mass Spectrometry Reviews, 2023 - Wiley Online Library
This Tutorial is to provide a summary of parameters useful for successful outcomes of
laserspray ionization (LSI) and related methods that employ a laser to ablate a matrix …

Soft ionization of saturated hydrocarbons, alcohols and nonpolar compounds by negative-ion direct analysis in real-time mass spectrometry

RB Cody, AJ Dane - Journal of the American Society for Mass …, 2013 - ACS Publications
Large polarizable n-alkanes (approximately C18 and larger), alcohols, and other nonpolar
compounds can be detected as negative ions when sample solutions are injected directly …