Macrophages are versatile immune cells with remarkable plasticity, enabling them to adapt
to diverse tissue microenvironments and perform various functions. Traditionally categorized …

Аbstract With increasing incidence and geography, cancer is one of the leading causes of
death, reduced quality of life and disability worldwide. Principal progress in the development …

Innate immunity plays an important role in host defense against pathogenic infections. It
involves macrophage polarization into either the pro-inflammatory M1 or the anti …

Specific protein 1 (Sp1) is central to regulating transcription factor activity and cell signaling
pathways. Sp1 is highly associated with the poor prognosis of various cancers; it is …

The emergence of immunotherapy has revolutionized the treatment landscape for various
types of cancer. Nevertheless, lung cancer remains one of the leading causes of cancer …

Tumor-associated macrophages (TAMs), fundamental constituents of the tumor
microenvironment (TME), significantly influence cancer development, primarily by promoting …

Lung cancer (LC) is one of the most common cancer worldwide. Tumor-associated
macrophages (TAMs) are important component of the tumor microenvironment (TME) and …

Rationale: Despite significant advances in precision treatments and immunotherapy, lung
cancer is the most common cause of cancer death worldwide. To reduce incidence and …

Background Our study aimed to elucidate the association between single nucleotide
polymorphisms (SNPs) in CYP2B6 gene and susceptibility to lung cancer (LC). Methods …

Globally, lung cancer stands as the leading type of cancer in terms of incidence and is the
major source of mortality attributed to cancer. We have outlined the molecular biomarkers for …