A review on phytochemical constituents and pharmacological potential of Calotropis procera

BD Wadhwani, D Mali, P Vyas, R Nair, P Khandelwal - RSC advances, 2021 - pubs.rsc.org
Calotropis procera is locally known as Aak or Madar in Hindi, milk weed in English and
belongs to the family Apocynaceae and subfamily Asclepiadoideae. Although a wasteland …

Anticancer and antiviral properties of cardiac glycosides: a review to explore the mechanism of actions

D Reddy, R Kumavath, D Barh, V Azevedo, P Ghosh - Molecules, 2020 - mdpi.com
Cardiac glycosides (CGs) have a long history of treating cardiac diseases. However, recent
reports have suggested that CGs also possess anticancer and antiviral activities. The …

Anticancer and immunogenic properties of cardiac glycosides

NFZ Schneider, C Cerella, CMO Simões, M Diederich - Molecules, 2017 - mdpi.com
Cardiac glycosides (CGs) are natural compounds widely used in the treatment of several
cardiac conditions and more recently have been recognized as potential antitumor …

Traditional West African pharmacopeia, plants and derived compounds for cancer therapy

WR Sawadogo, M Schumacher, MH Teiten… - Biochemical …, 2012 - Elsevier
Traditional pharmacopeia is strongly involved in the continuous search for the well being of
African populations. The World Health Organization (WHO) estimates that 80% of the …

Cardiac glycosides in cancer therapy: from preclinical investigations towards clinical trials

M Slingerland, C Cerella, HJ Guchelaar… - Investigational new …, 2013 - Springer
Cardiac glycosides have a long history in the treatment of cardiac disease. However, several
preclinical studies as well as two phase I studies have shown that cardenolides may also …

Emergence of cardiac glycosides as potential drugs: Current and future scope for cancer therapeutics

R Kumavath, S Paul, H Pavithran, MK Paul, P Ghosh… - Biomolecules, 2021 - mdpi.com
Cardiac glycosides are natural sterols and constitute a group of secondary metabolites
isolated from plants and animals. These cardiotonic agents are well recognized and …

Cardiac glycosides: From molecular targets to immunogenic cell death

M Diederich, F Muller, C Cerella - Biochemical Pharmacology, 2017 - Elsevier
Cardiac glycosides (CGs) are approved for the treatment of cardiovascular alterations and
their known cellular target is the alpha subunit of the sodium (Na+)/potassium (K+)-ATPase …

Bufadienolides from amphibians: A promising source of anticancer prototypes for radical innovation, apoptosis triggering and Na+/K+-ATPase inhibition

LQ De Sousa, K da Conceição Machado… - Toxicon, 2017 - Elsevier
Amphibians present pharmacologically active aliphatic, aromatic and heterocyclic molecules
in their skin as defense against microorganisms, predators and infections, such as steroids …

Prospects and therapeutic applications of cardiac glycosides in cancer remediation

JI Ayogu, AS Odoh - ACS Combinatorial Science, 2020 - ACS Publications
Active metabolites from natural sources are the predominant molecular targets in numerous
biological studies owing to their appropriate compatibility with biological systems and …

Anti-inflammatory and anticancer drugs from nature

B Orlikova, N Legrand, J Panning, M Dicato… - Advances in nutrition …, 2014 - Springer
Over the centuries, plant extracts have been used to treat various diseases. Until now,
natural products have played an important role in anticancer therapy as there are more than …