Critical roles for EPH receptor (EPH)–ephrin signalling in a range of chronic and
regenerative diseases are increasingly being recognized. In particular, the complex roles of …

The Eph receptor tyrosine kinases and ephrin ligands have been studied extensively for
their roles in developmental processes. In recent years, Eph receptors and ephrins have …

Recent evidence supports a role for EphB receptor tyrosine kinases as tumour suppressors
in colorectal and prostate cancer. However, it is unclear how these receptors inhibit cancer …

Eph receptor tyrosine kinases and their ephrin ligands are involved in various signalling
pathways and mediate critical steps of a wide variety of physiological and pathological …

Eph tyrosine kinase receptors and their ephrin ligands are expressed in most adult stem cell
niches and in many types of tumors. They maintain tissue homeostasis by controlling the …

Eph receptor tyrosine kinases play critical functions during development, in the formation of
tissue and organ borders, and the vascular and neural systems. Uniquely among tyrosine …

EphB4, a member of the largest family of receptor tyrosine kinases, is normally expressed on
endothelial and neuronal cells. Although aberrant expression of EphB4 has been reported …

Pre-clinical studies provide compelling evidence that Eph family receptor tyrosine kinases
(RTKs) and ligands promote cancer growth, neovascularization, invasion, and metastasis …

Erythropoietin-producing human hepatocellular receptors (EPHs) compose the largest
known subfamily of receptor tyrosine kinases (RTKs). They bind and interact with the EPH …

The ephrinA1 ligand exerts antioncogenic effects in tumor cells through activation and
downregulation of the EphA2 receptor and has been described as a membrane-anchored …