Exploring cell and tissue mechanics with optical tweezers

F Català-Castro, E Schäffer, M Krieg - Journal of cell science, 2022 - journals.biologists.com
Cellular and tissue biosystems emerge from the assembly of their constituent molecules and
obtain a set of specific material properties. To measure these properties and understand …

Mechanosensitive membrane proteins: Usual and unusual suspects in mediating mechanotransduction

MB Goodman, ES Haswell, V Vásquez - Journal of General Physiology, 2023 - rupress.org
This Viewpoint, which accompanies a Special Issue focusing on membrane
mechanosensors, discusses unifying and unique features of both established and emerging …

A MEC-2/stomatin condensate liquid-to-solid phase transition controls neuronal mechanotransduction during touch sensing

N Sanfeliu-Cerdán, F Català-Castro, B Mateos… - Nature Cell …, 2023 - nature.com
A growing body of work suggests that the material properties of biomolecular condensates
ensuing from liquid–liquid phase separation change with time. How this aging process is …

Neural engineering with photons as synaptic transmitters

M Porta-de-la-Riva, AC Gonzalez, N Sanfeliu-Cerdán… - Nature …, 2023 - nature.com
Neuronal computation is achieved through connections of individual neurons into a larger
network. To expand the repertoire of endogenous cellular communication, we developed a …

[PDF][PDF] FLInt: single shot safe harbor transgene integration via Fluorescent Landmark Interference

N Malaiwong, M Porta-De-La-Riva… - G3: Genes, Genomes …, 2023 - academic.oup.com
The stable incorporation of transgenes and recombinant DNA material into the host genome
is a bottleneck in many bioengineering applications. Due to the low efficiency, identifying the …

Biomotors, viral assembly, and RNA nanobiotechnology: Current achievements and future directions

L Rolband, D Beasock, Y Wang, YG Shu… - Computational and …, 2022 - Elsevier
Abstract The International Society of RNA Nanotechnology and Nanomedicine (ISRNN)
serves to further the development of a wide variety of functional nucleic acids and other …

[HTML][HTML] Optical tweezers for drug discovery

MTJ Halma, JA Tuszynski, GJL Wuite - Drug Discovery Today, 2023 - Elsevier
Highlights•Studying biomolecular folding with optical tweezers grants high dynamic
range.•Combining optical tweezers with molecular dynamics simulation enables accurate …

Can repetitive mechanical motion cause structural damage to axons?

A Coppini, A Falconieri, O Mualem… - Frontiers in Molecular …, 2024 - frontiersin.org
Biological structures have evolved to very efficiently generate, transmit, and withstand
mechanical forces. These biological examples have inspired mechanical engineers for …

Tailorable biosensors for real-time monitoring of stress distribution in soft biomaterials and living tissues

F Yuan, H Qi, B Song, Y Cui, J Zhang, H Liu… - Nature …, 2025 - nature.com
Visualizing mechanical stress distribution in soft and live biomaterials is essential for
understanding biological processes and improving material design. However, it remains …

Bio-inspired spreadable multi-signal self-sensing covering composite material for intelligent devices

D Chen, X Zhang, R Wang, Z Lin, G Li, Y Lei… - Composites …, 2024 - Elsevier
The spreadable materials with multi-sensing capabilities offer a wide range of application
possibilities. They can be applied directly to the surface of intelligent devices, facilitating the …