Human red blood cells (RBC) are highly differentiated cells that have lost all organelles and
most intracellular machineries during their maturation process. RBC are fundamental for the …

Human erythrocytes are organelle-free cells packaged with iron-containing hemoglobin,
specializing in the transport of oxygen. With a total number of approximately 25 trillion cells …

Recent work on selected aspects of the cellular and molecular physiology of cell volume
regulation is reviewed. First, the physiological significance of the regulation of cell volume is …

We have isolated a novel gene, hKCa4, encoding an intermediate conductance, calcium-
activated potassium channel from a human lymph node library. The translated protein …

Calcium-activated potassium channels modulate calcium signaling cascades and
membrane potential in both excitable and non-excitable cells. In this article we will review …

The hydrophobic lipid bitayer of the red cell membrane is nearly impermeable for hydrophilic
solutes. Nevertheless, the transport of CO2 in the blood involves a rapid exchange of HCO3 …

Polymers of deoxyhemoglobin S deform sickle cell anemia red blood cells into sickle
shapes, leading to the formation of dense, dehydrated red blood cells with a markedly …

A wide variety of calcium-activated K channels has been described and can be conveniently
separated into three classes based on differences in single-channel conductance, voltage …

Cae+-activated K+ currents are found in most types of cells. Considerable progress has
been made since the developement of single channel recording techniques m identifying …

Ca2+-dependent K+ efflux from human erythrocytes was first described in the 1950s.
Subsequent studies revealed that a K+-specific membrane protein (the Gárdos channel) …