Copper complexes as artificial DNA metallonucleases: from Sigman's reagent to next generation anti-cancer agent?

TJP McGivern, S Afsharpour, CJ Marmion - Inorganica Chimica Acta, 2018 - Elsevier
Platinum drugs continue to dominate medical oncology treatments but they have
shortcomings associated with their use including dose-limiting toxic side effects and …

Schiff base complexes, cancer cell lines, and anticancer evaluation: a review

SA Majid, JM Mir, G Jan, AH Shalla - Journal of Coordination …, 2022 - Taylor & Francis
This review examines the importance of Schiff base ligands and their metal complexes
against cancer. The chemotherapeutic action of certain metal complexes especially cisplatin …

Copper(II) N,N,O-Chelating Complexes as Potential Anticancer Agents

Q Peña, G Sciortino, JD Maréchal, S Bertaina… - Inorganic …, 2021 - ACS Publications
Three novel dinuclear Cu (II) complexes based on a N, N, O-chelating salphen-like ligand
scaffold and bearing varying aromatic substituents (− H,− Cl, and− Br) have been …

DNA-binding and in vitro cytotoxic activity of platinum (II) complexes of curcumin and caffeine

V Censi, AB Caballero, M Perez-Hernandez… - Journal of Inorganic …, 2019 - Elsevier
Three Pt (II) complexes containing the natural ligands curcumin and caffeine, namely [Pt
(curc)(PPh 3) 2] Cl (1),[PtCl (curc)(DMSO)](2)(curc= deprotonated curcumin) and trans-[Pt …

Synthesis, spectroscopic characterization, crystal structure and biological properties of novel co-crystal copper (II) complex containing dioxime ligand

CG Topkaya, ES Çetin, T Göktürk, S Kıncal… - Inorganic Chemistry …, 2023 - Elsevier
The title compound, co-crystal [(aqua)(1E, 1′ E, 2E, 2′ E)-2, 2′-(propane-1, 3-diylbis
(azaneylylidene)) bis (2-phenylacetaldehyde) dioximato] copper (II) chlorate,[Cu (HL 1) ClO …

Recent developments in the biological activities of 3d-metal complexes with salicylaldehyde-based N, O-donor Schiff base ligands

M Kumar, AK Singh, VK Singh, RK Yadav… - Coordination Chemistry …, 2024 - Elsevier
Schiff base ligands have received attention due to their versatile coordination abilities and
potential applications in medicinal and biological fields. This investigation offers an in-depth …

In vitro DNA interaction, topoisomerase I/II inhibition and cytotoxic properties of polymeric copper (II) complex bridged with perchlorate ion containing N4-type Schiff …

CG Topkaya, T Göktürk, T Hökelek, ES Cetin… - Journal of Molecular …, 2022 - Elsevier
Cu (II) complex containing p-Cl-isonitrosoacetophenone based on N 4-type Schiff base
ligand was synthesized and characterized by elemental analysis, FTIR, 1 H NMR, 13 C NMR …

Syntheses, structures and biological activities of square planar Ni (II), Cu (II) complexes

S Saha, S Jana, S Gupta, A Ghosh, HP Nayek - Polyhedron, 2016 - Elsevier
Abstract Ni (II) and Cu (II) complexes of a tridentate Schiff base ligand, N-(2-hydroxyphenyl)-
3-methoxy-salicylideneamine (H 2 L) have been synthesized and characterized by IR, NMR …

From solid state to in vitro anticancer activity of copper (II) compounds with electronically-modulated NNO Schiff base ligands

L Rigamonti, F Reginato, E Ferrari, L Pigani… - Dalton …, 2020 - pubs.rsc.org
The copper (II) complexes of general formula [Cu (GL)(Cl)](1–3, G= OMe, H and NO2,
respectively), bearing tridentate Schiff base ligands (GL−) and a chloride as a fourth labile …

An insight into the Effect of Schiff Base and their d and f Block Metal complexes on various Cancer cell lines as Anticancer agents: a review

Presenjit, S Chaturvedi, A Singh… - Anti-Cancer Agents …, 2024 - benthamdirect.com
Over the last few decades, an alarming rise in the percentage of individuals with cancer and
those with multi-resistant illnesses has forced researchers to explore possibilities for novel …