The endothelium is immunoregulatory in that inhibiting the function of vascular adhesion
molecules blocks leukocyte recruitment and thus tissue inflammation. The function of …

RA is a debilitating disorder that manifests as chronic localized synovial and systemic
inflammation leading to progressive joint destruction. Recent advances in the molecular …

抄録 Peroxiredoxins possess thioredoxin or glutathione peroxidase and chaperone-like
activities and thereby protect cells from oxidative insults. Recent studies, however, reveal …

Rheumatoid arthritis (RA) is the most common autoimmune articular disorder. It is
characterized by chronic inflammation and progressive joint destruction. As research …

Objectives Knee joint distraction (KJD) is a novel, but poorly understood, treatment for
osteoarthritis (OA) associated with remarkable 'spontaneous' cartilage repair in which …

Simple Summary Cardiovascular diseases are the first cause of morbimortality worldwide.
They are mainly caused by atherosclerosis, with progressive plaque formation in the arterial …

Rheumatoid arthritis (RA) is a chronic autoimmune mediated joint disease with severe
complications affecting 1% of the population worldwide. Although the exact mechanism …

Cardiac fibroblasts (CF) act as sentinel cells responding to chemokines, cytokines and
growth factors released in cardiac tissue in cardiac injury events, such as myocardial …

Fatty acids (FAs) are potent organic compounds that not only can be used as an energy
source during nutrient deprivation but are also involved in several essential signaling …

Objective—Inhibition of HMGCR (3-hydroxy-3-methylglutaryl-coenzyme A reductase) is
atheroprotective primarily by decreasing plasma LDL (low-density lipoprotein)-cholesterol …