Favipiravir, an anti-influenza drug against life-threatening RNA virus infections
K Shiraki, T Daikoku - Pharmacology & therapeutics, 2020 - Elsevier
Favipiravir has been developed as an anti-influenza drug and licensed as an anti-influenza
drug in Japan. Additionally, favipiravir is being stockpiled for 2 million people as a …
drug in Japan. Additionally, favipiravir is being stockpiled for 2 million people as a …
Lassa fever—the road ahead
RF Garry - Nature Reviews Microbiology, 2023 - nature.com
Lassa virus (LASV) is endemic in the rodent populations of Sierra Leone, Nigeria and other
countries in West Africa. Spillover to humans occurs frequently and results in Lassa fever, a …
countries in West Africa. Spillover to humans occurs frequently and results in Lassa fever, a …
[HTML][HTML] Why does viral RNA sometimes persist after recovery from acute infections?
DE Griffin - PLoS biology, 2022 - journals.plos.org
DNA viruses often persist in the body of their host, becoming latent and recurring many
months or years later. By contrast, most RNA viruses cause acute infections that are cleared …
months or years later. By contrast, most RNA viruses cause acute infections that are cleared …
Favipiravir as a potential countermeasure against neglected and emerging RNA viruses
Favipiravir, also known as T-705, is an antiviral drug that has been approved in 2014 in
Japan to treat pandemic influenza virus infections. The drug is converted intracellularly into …
Japan to treat pandemic influenza virus infections. The drug is converted intracellularly into …
[HTML][HTML] The breadth of viruses in human semen
Zika virus RNA is frequently detected in the semen of men after Zika virus infection. To learn
more about persistence of viruses in genital fluids, we searched PubMed for relevant …
more about persistence of viruses in genital fluids, we searched PubMed for relevant …
Favipiravir in therapy of viral infections
R Łagocka, V Dziedziejko, P Kłos, A Pawlik - Journal of clinical medicine, 2021 - mdpi.com
Favipiravir (FPV) is a novel antiviral drug acting as a competitive inhibitor of RNA-dependent
RNA polymerase (RdRp), preventing viral transcription and replication. FPV was approved …
RNA polymerase (RdRp), preventing viral transcription and replication. FPV was approved …
From ancient to emerging infections: the odyssey of viruses in the male genital tract
A Le Tortorec, G Matusali, D Mahé… - Physiological …, 2020 - journals.physiology.org
The male genital tract (MGT) is the target of a number of viral infections that can have
deleterious consequences at the individual, offspring, and population levels. These …
deleterious consequences at the individual, offspring, and population levels. These …
Lassa fever: epidemiology, clinical features, diagnosis, management and prevention
Lassa fever, is an acute zoonotic disease of humans that is mainly endemic to West African
countries of Guinea, Liberia, Nigeria, and Sierra Leone. 1–3 Other countries such as Mali …
countries of Guinea, Liberia, Nigeria, and Sierra Leone. 1–3 Other countries such as Mali …
A human monoclonal antibody combination rescues nonhuman primates from advanced disease caused by the major lineages of Lassa virus
RW Cross, ML Heinrich, KA Fenton… - Proceedings of the …, 2023 - National Acad Sciences
There are no approved treatments for Lassa fever (LF), which is responsible for thousands of
deaths each year in West Africa. A major challenge in developing effective medical …
deaths each year in West Africa. A major challenge in developing effective medical …
Broad-spectrum antiviral agents: a crucial pandemic tool
A Adalja, T Inglesby - Expert review of Anti-infective Therapy, 2019 - Taylor & Francis
Among the myriad infectious disease threats humans face from bacteria, prions, parasites,
protozoa, fungi, ectoparasites, and viruses, it is viral infections that arguably constitute the …
protozoa, fungi, ectoparasites, and viruses, it is viral infections that arguably constitute the …