[HTML][HTML] Male infertility and oxidative stress: a focus on the underlying mechanisms

RJ Aitken, JR Drevet, A Moazamian, P Gharagozloo - Antioxidants, 2022 - mdpi.com
Reactive oxygen species (ROS) play a critical role in defining the functional competence of
human spermatozoa. When generated in moderate amounts, ROS promote sperm …

Oxidative stress and male infertility: current knowledge of pathophysiology and role of antioxidant therapy in disease management

E Barati, H Nikzad, M Karimian - Cellular and Molecular Life Sciences, 2020 - Springer
Infertility is a global health problem involving about 15% of couples. Approximately half of
the infertility cases are related to male factors. The oxidative stress, which refers to an …

Advances in cryopreservation of bull sperm

MR Ugur, A Saber Abdelrahman, HC Evans… - Frontiers in veterinary …, 2019 - frontiersin.org
Cryopreservation of semen and artificial insemination have an important, positive impact on
cattle production, and product quality. Through the use of cryopreserved semen and artificial …

[HTML][HTML] Male subfertility and oxidative stress

EPP Evans, JTM Scholten, A Mzyk… - Redox biology, 2021 - Elsevier
To date 15% of couples are suffering from infertility with 45–50% of males being
responsible. With an increase in paternal age as well as various environmental and lifestyle …

The importance of oxidative stress in determining the functionality of mammalian spermatozoa: a two-edged sword

RJ Aitken, JR Drevet - Antioxidants, 2020 - mdpi.com
This article addresses the importance of oxidative processes in both the generation of
functional gametes and the aetiology of defective sperm function. Functionally, sperm …

Mitochondria functionality and sperm quality

A Amaral, B Lourenço, M Marques… - …, 2013 - rep.bioscientifica.com
Although mitochondria are best known for being the eukaryotic cell powerhouses, these
organelles participate in various cellular functions besides ATP production, such as calcium …

The paradoxical relationship between stallion fertility and oxidative stress

Z Gibb, SR Lambourne, RJ Aitken - Biology of reproduction, 2014 - academic.oup.com
The relationship between stallion fertility and oxidative stress remains poorly understood.
The purpose of this study was to identify criteria for thoroughbred fertility assessment by …

Oxidative stress and human spermatozoa: diagnostic and functional significance of aldehydes generated as a result of lipid peroxidation

R Moazamian, A Polhemus… - MHR: Basic science …, 2015 - academic.oup.com
Oxidative stress is known to compromise human sperm function and to activate the intrinsic
apoptotic cascade in these cells. One of the key features of oxidatively stressed …

Selection of functional human sperm with higher DNA integrity and fewer reactive oxygen species

W Asghar, V Velasco, JL Kingsley… - Advanced …, 2014 - Wiley Online Library
Fertilization and reproduction are central to the survival and propagation of a species.
Couples who cannot reproduce naturally have to undergo in vitro clinical procedures. An …

Redox regulation and oxidative stress: The particular case of the stallion spermatozoa

FJ Peña, C O'Flaherty, JM Ortiz Rodríguez… - Antioxidants, 2019 - mdpi.com
Redox regulation and oxidative stress have become areas of major interest in spermatology.
Alteration of redox homeostasis is recognized as a significant cause of male factor infertility …