Extraction and application of keratin from natural resources: a review

CR Chilakamarry, S Mahmood, SNBM Saffe… - 3 Biotech, 2021 - Springer
Over recent years, keratin has gained great popularity due to its exceptional biocompatible
and biodegradable nature. It has shown promising results in various industries like poultry …

Whole-organ genomic characterization of mucosal field effects initiating bladder carcinogenesis

T Majewski, H Yao, J Bondaruk, W Chung, S Lee… - Cell reports, 2019 - cell.com
We used whole-organ mapping to study the locoregional molecular changes in a human
bladder containing multifocal cancer. Widespread DNA methylation changes were identified …

Phosphorylated nuclear DICER1 promotes open chromatin state and lineage plasticity of AT2 tumor cells in lung adenocarcinomas

RA Reyes-Castro, SY Chen, J Seemann, ST Kundu… - Science …, 2023 - science.org
KRAS/ERK pathway phosphorylates DICER1, causing its nuclear translocation, and
phosphomimetic Dicer1 contributes to tumorigenesis in mice. Mechanisms through which …

Rpb4/7, a key element of RNA pol II to coordinate mRNA synthesis in the nucleus with cytoplasmic functions in Saccharomyces cerevisiae

AI Garrido-Godino, M Martín-Expósito… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Gene expression is a complex phenomenon that depends on multiple protein complexes,
including RNA polymerases (RNA pols). In eukaryotes, bacteria, and archaea, RNA pols are …

Transcriptional investigation of the toxic mechanisms of perfluorooctane sulfonate in rats based on an RNA-Seq approach

T Wang, X Zhao, T Liu, J Zhang, J Qiu, M Li, R Weng - Chemosphere, 2023 - Elsevier
Perfluorooctane sulfonate (PFOS) was widely used in industrial applications before it was
listed as a persistent organic pollutant by the Conference of the Parties in the Stockholm …

RNA polymerase II subunit D is essential for zebrafish development

M Maeta, M Kataoka, Y Nishiya, K Ogino, M Kashima… - Scientific Reports, 2020 - nature.com
Abstract DNA-directed RNA polymerase II (pol II) is composed of ten core and two
dissociable subunits. The dissociable subcomplex is a heterodimer of Rpb4/Polr2d and …

A comparative study of the proteome regulated by the Rpb4 and Rpb7 subunits of RNA polymerase II in fission yeast

D Kumar, S Varshney, S Sengupta, N Sharma - Journal of proteomics, 2019 - Elsevier
RNA polymerase II is a conserved multi-subunit enzyme made up of twelve different
subunits. Two of these subunits, Rpb4 and Rpb7, have been shown to perform functions in …

Genome-wide transcriptional response to altered levels of the Rpb7 subunit of RNA polymerase II identifies its role in DNA damage response in Schizosaccharomyces …

D Kumar, N Sharma - FEMS yeast research, 2019 - academic.oup.com
Transcription of protein-coding genes is a highly regulated process. In eukaryotes, it
involves cross-talk between the RNA polymerase II enzyme and different proteins of the …

Fine tuning of Rpb4 phosphorylation modulates Rpb4/7 stoichiometry within yeast RNA polymerase II and regulates gene expression

A González-Jiménez, MC González-Jiménez… - bioRxiv, 2023 - biorxiv.org
Abstract RNA polymerase II (RNAPII) consists of 12 subunits, including Rpb4 and Rpb7,
which form a heterodimeric stalk domain. In yeast, assembly of Rpb4/7 with the 10-subunit …

[HTML][HTML] Outcome of gastric gastrointestinal stromal tumors at National Cancer Institute, Cairo University

SS Shaeir, MT Fouad, F Shafeik… - The Egyptian Journal …, 2023 - journals.lww.com
Background The purpose of this research was to inspect the tumor landscapes, surgical
particulars, and survival distribution of patients of gastric gastrointestinal stromal tumors …