Background: Peptidyl arginine deiminase 4 (PAD4) is an enzyme that converts arginine into
citrulline. PAD4 is expressed in neutrophils that, when activated, can drive the formation of …

The severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) had spread from
China and, within 2 months, became a global pandemic. The infection from this disease can …

The generation of post-translational modifications (PTMs) in human proteins is a
physiological process leading to structural and immunologic variety in proteins, with …

Posttranslational protein modifications (PTMs) are an inherent response to physiological
changes causing altered protein structure and potentially modulating important biological …

Background Citrullination is the post-translational conversion of arginine into citrulline in
proteins. The reaction is catalyzed by peptidylarginine deiminase (PAD), of which five …

Citrullination is a post-translation modification of proteins, where the proteinaceous arginine
residues are converted to non-coded citrulline residues. The immune tolerance to such …

Abstract Peptidyl arginine deiminase 4 (PAD4) plays a critical role in many autoimmune
diseases including rheumatoid arthritis. Herein, a trypsin assisted highly immunoassay …

Thioredoxin-interacting protein (TXNIP) negatively effects the redox state and growth
signaling via its interactions with thioredoxin (TRX) and regulated in development and DNA …

Protein citrullination is a post-translational modification of arginine that controls a diverse
array of cellular processes, including gene regulation, protein stability, and neutrophil …

The formation of elastic fibers is active only in the perinatal period. How elastogenesis is
developmentally regulated is not fully understood. Citrullination is a unique form of post …