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Development of idiosyncratic hepatotoxicity is an intricate process involving both concurrent
as well as sequential events determining the direction of the pathways, degree of liver injury …

Pediatric acute liver failure (PALF) is a rare, rapidly progressive clinical syndrome with
significant morbidity and mortality. The phenotype of PALF manifests as abrupt onset liver …

Oxidative stress is a key pathological feature implicated in both acute and chronic liver
diseases, including drug‐induced liver injury (DILI). The latter describes hepatic injury …

Background Treatment of drug susceptible tuberculosis (DS-TB) requires regimens
containing first line drugs (FLDs') whereas drug resistant tuberculosis (DR-TB) are treated …

Idiosyncratic drug-induced liver injury (DILI) is an important cause of morbidity and mortality
following drugs taken in therapeutic doses. Hepatotoxicity is a leading cause of attrition in …

Background & Aims Several prognostic factors are used to identify patients with acute liver
failure (ALF) who require emergency liver transplantation. We performed a meta-analysis to …

Background Etiology of and outcomes following idiosyncratic drug-induced liver injury (DILI)
vary geographically. We conducted a prospective study of DILI in India, from 2013 to 2018 …

Acute liver failure (ALF) requires urgent attention to identify etiology and determine
prognosis, in order to assess likelihood of survival or need for transplantation. Identifying …

Abstract Background and Aims Anti‐tuberculosis drugs remain as an important cause of
drug‐induced liver injury (DILI) worldwide. Adverse drug reactions reduce the effectiveness …