Astrocyte differentiation of human pluripotent stem cells: new tools for neurological disorder research

A Chandrasekaran, HX Avci, M Leist… - Frontiers in cellular …, 2016 - frontiersin.org
Astrocytes have a central role in brain development and function, and so have gained
increasing attention over the past two decades. Consequently, our knowledge about their …

Astrocytic β2-adrenergic receptors: From physiology to pathology

G Laureys, R Clinckers, S Gerlo, A Spooren… - Progress in …, 2010 - Elsevier
Evidence accumulates for a key role of the β2-adrenergic receptors in the many homeostatic
and neuroprotective functions of astrocytes, including glycogen metabolism, regulation of …

Reduction in paracrine Wnt3 factors during aging causes impaired adult neurogenesis

M Okamoto, K Inoue, H Iwamura… - The FASEB …, 2011 - Wiley Online Library
The mammalian brain contains neural stem cells (NSCs) that enable continued
neurogenesis throughout adulthood. However, NSC function and/or numbers decline with …

Proteomic analysis of mouse astrocytes and their secretome by a combination of FASP and StageTip‐based, high pH, reversed‐phase fractionation

D Han, J Jin, J Woo, H Min, Y Kim - Proteomics, 2014 - Wiley Online Library
Astrocytes are the most abundant cells in the CNS, but their function remains largely
unknown. Characterization of the whole‐cell proteome and secretome in astrocytes would …

[HTML][HTML] BYSL contributes to tumor growth by cooperating with the mTORC2 complex in gliomas

S Gao, Z Sha, J Zhou, Y Wu, Y Song, C Li… - Cancer Biology & …, 2021 - ncbi.nlm.nih.gov
Objective: BYSL, which encodes the Bystin protein in humans, is upregulated in reactive
astrocytes following brain damage and/or inflammation. We aimed to determine the role and …

Identification of protein biomarkers for schizophrenia and bipolar disorder in the postmortem prefrontal cortex using SELDI-TOF-MS ProteinChip profiling combined …

SI Novikova, F He, NJ Cutrufello, MS Lidow - Neurobiology of Disease, 2006 - Elsevier
This paper describes the high-throughput proteomic analysis of the dorsolateral prefrontal
cortex (DLPFC) from schizophrenia (SCHIZ), bipolar (BD), and normal control cohorts from …

Role of gap junction protein connexin43 in astrogliosis induced by brain injury

N Theodoric, JF Bechberger, CC Naus, WC Sin - 2012 - journals.plos.org
Astrogliosis is a process that involves morphological and biochemical changes associated
with astrocyte activation in response to cell damage in the brain. The upregulation of …

Purity, cell viability, expression of GFAP and bystin in astrocytes cultured by different procedures

F Du, ZM Qian, L Zhu, XM Wu, C Qian… - Journal of cellular …, 2010 - Wiley Online Library
Primary astrocyte cultures are the most commonly used in vitro model for neurobiological
studies. We speculated that different protocols might induce differences not only in the …

[PDF][PDF] Apomorphine‐induced activation of dopamine receptors modulates FGF‐2 expression in astrocytic cultures and promotes survival of dopaminergic neurons

A Li, H Guo, X Luo, J Sheng, S Yang, Y Yin, J Zhou… - The FASEB journal, 2006 - Citeseer
Apomorphine (APO), a potent D1/D2 dopamine receptor agonist, is currently in use as an
antiparkinsonian drug. We investigated the molecular mechanism underlying APO-induced …

Zebrafish midbrain slow-amplifying progenitors exhibit high levels of transcripts for nucleotide and ribosome biogenesis

G Recher, J Jouralet, A Brombin, A Heuzé… - …, 2013 - journals.biologists.com
Investigating neural stem cell (NSC) behaviour in vivo, which is a major area of research,
requires NSC models to be developed. We carried out a multilevel characterisation of the …