The reaction of variously substituted 1, 2, 4-triazole derivatives with morpholine and
formaldehyde represents an efficient and easy-to-set synthetic entry toward heterocyclic N …

In this study, a series of novel Schiff bases (4a-4h) containing 1, 2, 4-triazole structure were
synthesized through a condensation reaction of 3-alkyl (aryl)-4-amino-4, 5-dihydro-1 H-1, 2 …

In this study, some important ADME parameters such as physicochemical properties,
lipophilicity, water solubility, pharmacokinetics, medicinal chemistry and drug-likeness …

3-Alkyl (aryl)-4-amino-4, 5-dihydro-1 H-1, 2, 4-triazol-5-ones 2a-g reacted with4-
diethylaminobenzaldehyde to afford the corresponding 3-alkyl (aryl)-4-(4-diethyl …

The marine sponge Neopetrosia exigua is known as a goldmine of novel compounds, yet its
pharmacological activities remain poorly characterised. Herein, this study investigates the …

Six novel 3-alkyl (aryl)-4-(p-nitrobenzoylamino)-4, 5-dihydro-1 H-1, 2, 4-triazol-5-ones (2a-f)
were synthesized by the reactions of 3-alkyl (aryl)-4-amino-4, 5-dihydro-1 H-1, 2, 4-triazol-5 …

In this study, molecular geometric optimization of five 4, 5-dihydro-1H-1, 2, 4-triazol-5-one
derivative compounds was obtained using Density Functional Theory,(DFT, B3LYP)/Hartree …

Alkyl (aryl)-4-amino-4, 5-dihydro-1H-1, 2, 4-triazol-5-ones (2) reacted with 4-
benzenesulfonyloxybenzaldehyde (3) to afford the corresponding seven novel 3-alkyl (aryl) …

Benzimidazoles and their derivatives including imidazole are studied widely because they
exist in the structure of natural products and different drugs. pKa values are extremely …

Abstract The protonation process of 1, 2, 4-triazoline-3-thiones (T3T) was studied in
aqueous sulfuric acid using the UV method. Characteristic vector analysis (CVA) was used …