Excitotoxicity, the specific type of neurotoxicity mediated by glutamate, may be the missing
link between ischemia and neuronal death, and intervening the mechanistic steps that lead …

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Recent studies suggest that excitatory amino acids (EAAs) have a wide variety of
physiological and pathophysiological roles during central nervous system (CNS) …

The role of seizures occurring with perinatal hypoxic‐ischemic encephalopathies is unclear.
We examined the relationships between the time course of parasagittal …

We evaluated whether regional differences in the magnitude of glutamate, γ‐aminobutyric
acid (GABA), and glycine release could explain why some regions are vulnerable to …

Induction of the 70-kDa heat shock protein, hsp70, has been demonstrated in brain following
experimental stroke. In the present study, hsp70 was localized in gerbil brain at intervals …

An important feature of ischemic brain damage is the exceptional vulnerability of specific
neuronal populations and the relative resistance of others. Silver impregnation was used to …

When the brain temperature was lowered by 2° C from normothermic temperature, a
protective effect on postischemic neuronal death was exhibited and levels of extracellular …

The ultrastructural changes in the pyramidal neurons of the CA1 region of the hippocampus
were studied 6 h, 24 h, 48 h, and 72 h following a transient 10 min period of cerebral …

Glutamatergic transmission is an important factor in the development of neuronal death
following transient cerebral ischemia. In this investigation the effects of N-methyl-d-aspartate …