MicroRNAs (miRNAs) bind to complementary target RNAs and regulate their gene
expression post-transcriptionally. These non-coding regulatory RNAs become functional …

Obsessive-compulsive and related disorders (OCRD) is an emergent class of psychiatric
illnesses that contributes substantially to the global mental health disease burden. In …

SET domain-containing 5 (SETD5) is an uncharacterized member of the protein lysine
methyltransferase family and is best known for its transcription machinery by methylating …

Obsessive-compulsive disorder (OCD) is a chronic, severe psychiatric disorder that has
been ranked by the World Health Organization as one of the leading causes of illness …

Animals often behave repetitively and predictably. These repetitive behaviors can have a
component that is learned and ingrained as habits, which can be evolutionarily …

Background Trichotillomania (TTM) and excoriation disorder (ED) are impairing obsessive-
compulsive related disorders that are common in the general population and for which there …

Due to limited samples, no genetic loci have been identified for obsessive-compulsive
disorder (OCD) in genome-wide association studies. Additionally, although co-morbidities …

Once thought to be rare, autism spectrum disorder (ASD) is now diagnosed more frequently
than intellectual disability and cerebral palsy combined. There has been a temporal change …

Clinical neurosciences, and psychiatry specifically, have been challenged by the lack of a
comprehensive and practical framework that explains the core mechanistic processes of …

GATA zinc finger domain containing 2A (GATAD2A) is a subunit of the nucleosome
remodeling and deacetylase (NuRD) complex. NuRD is known to regulate gene expression …