The MODOMICS database was updated with recent data and now includes new data types
related to RNA modifications. Changes to the database include an expanded modification …

Abstract N 6-methyladenosine (m6A) in eukaryotes is the most common and widespread
internal modification in mRNA. The modification regulates mRNA stability, translation …

The mitoribosome regulates cellular energy production, and its dysfunction is associated
with aging. Inhibition of the mitoribosome can be caused by off-target binding of …

Aberrant RNA modifications can lead to dysregulated gene expression and impeded growth
in plants. Ribosomal RNA (rRNA) constitutes a substantial portion of total RNA, while the …

In plant cells, translation occurs in three compartments: the cytosol, the plastids and the
mitochondria. While the structures of the (prokaryotic-type) ribosomes in plastids and …

Protein synthesis by the ribosome requires large-scale rearrangements of the 'small'subunit
(SSU;∼ 1 MDa), including inter-and intra-subunit rotational motions. However, with nearly …

The chloroplast and mitochondrion are semi-autonomous organelles that play essential
roles in cell function. These two organelles are embellished with prokaryotic remnants and …

The ribosomal core is universally conserved across the tree of life. However, eukaryotic
ribosomes contain diverse rRNA expansion segments (ESs) on their surfaces. Sites of ES …

The ribosomal RNA of the human protein synthesis machinery comprises numerous
chemical modifications that are introduced during ribosome biogenesis. Here we present the …

Abstract mRNA translation is tightly regulated by various classes of RNA-binding proteins
(RBPs) during development and in response to changing environmental conditions. In this …