Barriers to clinical adoption of pharmacogenomic testing in psychiatry: a critical analysis

CR Virelli, AG Mohiuddin, JL Kennedy - Translational psychiatry, 2021 - nature.com
Pharmacogenomics (PGx) is the study of genetic influences on an individual's response to
medications. Improvements in the quality and quantity of PGx research over the past two …

Oral Janus kinase inhibitors for atopic dermatitis

D Mikhaylov, B Ungar, Y Renert-Yuval… - Annals of Allergy …, 2023 - Elsevier
Atopic dermatitis (AD) is one of the most common inflammatory skin conditions. The
pathogenesis of AD involves skin barrier disruption and immune activation of T-helper (TH) …

[HTML][HTML] The current state of laboratory mycology in Asia/Pacific: a survey from the European Confederation of Medical Mycology (ECMM) and International Society for …

J Salmanton-García, WY Au, M Hoenigl… - International journal of …, 2023 - Elsevier
Abstract Introduction: Invasive fungal infections (IFIs) in Asia/Pacific are a particular threat to
patients with malignancies, uncontrolled diabetes mellitus or undiagnosed/untreated human …

The Frequency of Major CYP2C19 Genetic Polymorphisms in Women of Asian, Native Hawaiian and Pacific Islander Subgroups

KY Alrajeh, YM Roman - Personalized Medicine, 2022 - Taylor & Francis
Aim: Prevalence of clinically actionable genetic variants of CYP2C19 is lacking in specific
population subgroups. This study aims to assess the frequencies of CYP2C19* 2,* 3, and …

Implementation of pre‐emptive testing of a pharmacogenomic panel in clinical practice: Where do we stand?

E Peruzzi, R Roncato, E De Mattia… - British Journal of …, 2023 - Wiley Online Library
Adverse drug reactions (ADRs) account for a large proportion of hospitalizations among
adults and are more common in multimorbid patients, worsening clinical outcomes and …

[HTML][HTML] Obesity pillars roundtable: obesity and East Asians

HE Bays, J Ng, J Sicat, M Look - Obesity Pillars, 2022 - Elsevier
Abstract Background Individuals from East Asia make up about 1/5 th of the world's
population. Individuals from South Asia with obesity are well-described to have increased …

Reconstructing the ancestral gene pool to uncover the origins and genetic links of Hmong–Mien speakers

Y Gao, X Zhang, H Chen, Y Lu, S Ma, Y Yang, M Zhang… - BMC biology, 2024 - Springer
Abstract Background Hmong–Mien (HM) speakers are linguistically related and live
primarily in China, but little is known about their ancestral origins or the evolutionary …

Ethnic diversity and warfarin pharmacogenomics

IG Asiimwe, M Pirmohamed - Frontiers in pharmacology, 2022 - frontiersin.org
Warfarin has remained the most commonly prescribed vitamin K oral anticoagulant
worldwide since its approval in 1954. Dosing challenges including having a narrow …

Assessment of clinically actionable pharmacogenetic markers to stratify anti-seizure medications

D Guin, Y Hasija, R Kukreti - The Pharmacogenomics Journal, 2023 - nature.com
Epilepsy treatment is challenging due to heterogeneous syndromes, different seizure types
and higher inter-individual variability. Identification of genetic variants predicting drug …

A clinical pharmacology and therapeutics Teacher's guide to race‐based medicine, inclusivity, and diversity

MJ Bakkum, P Verdonk, EG Thomas… - Clinical …, 2023 - Wiley Online Library
The relationship between race and biology is complex. In contemporary medical science,
race is a social construct that is measured via self‐identification of study participants. But …