The generation of human cardiomyocytes (CMs) from human pluripotent stem cells (hPSCs)
has become an important resource for modeling human cardiac disease and for drug …

Induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) hold enormous potential
in many fields of cardiovascular research. Overcoming many of the limitations of their …

Background: Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs)
have emerged as a promising experimental tool for translational heart research and drug …

Abstract Background Mesenchymal stem cells (MSCs) have potent immunomodulatory
effects on multiple immune cells and have great potential in treating immune disorders …

The sarcomere is the contractile unit within cardiomyocytes driving heart muscle contraction.
We sought to test the mechanisms regulating actin and myosin filament assembly during …

Models based on human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM)
are proposed in almost any field of physiology and pharmacology. The development of …

Tight regulation of the Na/K pump is essential for cellular function because this heteromeric
protein builds and maintains the electrochemical gradients for Na+ and K+ that energize …

In fibroblasts, large Ca transients activate massive endocytosis (MEND) that involves
membrane protein palmitoylation subsequent to mitochondrial permeability transition pore …

Ten years ago Yamanaka's lab identified a way to reprogram terminally differentiated cells to
a pluripotent state, similar to that of embryonic stem cell. This procedure opened the road for …

Rationale: CAV3 (caveolin3) variants associated with arrhythmogenic cardiomyopathy and
muscular dystrophy can disrupt post-Golgi surface trafficking. As CAV1 (caveolin1) was …