The expression and function of the basic helix-loop-helix (bHLH) transcription factor NeuroD
were studied in the developing neural retina in rodent. neuroD was expressed in areas of …

Neuronal cell fate decisions are directed in Drosophila by NUMB, a signaling adapter
protein with two protein–protein interaction domains: a phosphotyrosine-binding domain …

Measuring neuroactivity underlying complex behaviors facilitates understanding the
microcircuitry that supports these behaviors. We have developed a functional and molecular …

In the Chx10-null ocular retardation (orJ) mouse, retinal progenitor cell (RPC) proliferation is
impaired, and bipolar neurons, a late born cell type, fail to differentiate. It is unclear whether …

Photoacoustic tomography (PAT) is a molecular imaging technology. Unlike conventional
reporter gene imaging, which is usually based on fluorescence, photoacoustic reporter gene …

Concern regarding the use of variola and monkeypox viruses as bioterrorist agents has led
to an increased study of orthopoxviruses to understand the molecular and cellular basis of …

Adenovirus-mediated gene transfer is a potential method for enhancing tendon healing. We
investigated the transfection of Ad5CMVntLacZ, an adenovirus containing the reporter gene …

Conditional transgenic mouse models are important tools for investigations of
neurodegenerative diseases and evaluation of potential therapeutic interventions. A popular …

We present a digital atlas system that allows mapping of molecular expression patterns at
cellular resolution through large series of histological sections. Using this system, we have …

There are many applications in which retrovirus vectors are used as transduction agents. In
some cases, the vector carries a gene that one wishes to express in a target cell in order to …