M Asanuma, I Miyazaki - International journal of molecular sciences, 2021 - mdpi.com
Glutathione (GSH) is the most abundant intrinsic antioxidant in the central nervous system, and its substrate cysteine readily becomes the oxidized dimeric cystine. Since neurons lack …
Y Wei, M Lu, M Mei, H Wang, Z Han, M Chen… - Nature …, 2020 - nature.com
Oxidative stress is a major pathogenic mechanism in Parkinson's disease (PD). As an important cellular antioxidant, glutathione (GSH) balances the production and incorporation …
Cognitive impairments are pervasive and persistent sequelae of human traumatic brain injury (TBI). In vivo models of TBI, such as the controlled cortical impact (CCI) and fluid …
ME Haque, M Asanuma, Y Higashi, I Miyazaki… - … et Biophysica Acta (BBA …, 2003 - Elsevier
Neurotoxic properties of l-dopa and dopamine (DA)-related compounds were assessed in human neuroblastoma SH-SY5Y cells with reference to their structural relationship. l-Dopa …
CB Aiken - Journal of Clinical Psychiatry, 2007 - psychiatrist.com
To estimate short-term rates of intolerable side effects and psychosis, data from all treated subjects in prospective and retrospective studies of depression (253 subjects from 8 studies) …
C Buhmann, S Arlt, A Kontush, T Möller-Bertram… - Neurobiology of …, 2004 - Elsevier
We determined systemic oxidative stress in Parkinson's disease (PD) patients, patients with other neurological diseases (OND) and healthy controls by measurement of in vitro …
K Radad, G Gille, WD Rausch - Pharmacol Rep, 2005 - if-pan.krakow.pl
Parkinson's disease (PD) is a chronic and progressive neurological disorder characterized by selective degeneration of dopaminergic neurons (DAergic) in the substantia nigra pars …
S Morimoto, S Takahashi, K Fukushima, H Saya… - Regenerative …, 2019 - Elsevier
Introduction Amyotrophic lateral sclerosis (ALS) is an intractable and incurable neurological disease. It is a progressive disease characterized by muscle atrophy and weakness caused …
AE Kline, JL Massucci, X Ma, RD Zafonte… - Journal of …, 2004 - liebertpub.com
Oxidative stress is a significant contributor to the secondary sequelae of traumatic brain injury (TBI), and may mediate subsequent neurobehavioral deficits and histopathology. The …