The defining feature of the Gram-negative cell envelope is the presence of two cellular
membranes, with the specialized glycolipid lipopolysaccharide (LPS) exclusively found on …

The outer membrane (OM) of Gram-negative bacteria provides an efficient barrier against
external noxious compounds such as antimicrobial agents. Associated with drug target …

Klebsiella pneumoniae is an opportunistic bacterial pathogen leading to life-threatening
nosocomial infections. Emergence of highly resistant strains poses a major challenge in the …

Food preservation is a schematic and scientific procedure employed for the maintenance
and improvement of food's quality, shelf life, and nutritional value. Although, on one hand …

One of the global challenges of the 21st century is the increase in mortality from infectious
diseases against the backdrop of the spread of antibiotic-resistant pathogenic …

Multidrug resistance in Pseudomonas aeruginosa is a noticeable and ongoing major
obstacle for inhibitor design. In P. aeruginosa, uridine diphosphate N-acetylglucosamine …

2S albumin is a low-molecular-weight seed storage protein belonging to the prolamin
superfamily. In the present work a small 2S albumin (WTA) protein of~ 16 kDa has been …

Background Acinetobacter baumannii is a highly antimicrobial resistant nosocomial
pathogen. Resistance to currently used antibiotics has limited effective drugs against this …

The enoyl-acyl carrier protein reductase (ENR) is an established drug target and catalyzes
the last reduction step of the fatty acid elongation cycle. Here, we report the crystal structures …

Gram-negative bacteria show more drug-resistant than Gram-positive bacteria due to unique
structural attribute and cause significant morbidity and mortality across the globe. Such …