Atrial septal defects (ASD) are a common congenital heart defect. The majority of patient
with ASDs often follow an uncomplicated course of events. However, a proportion of patients …

Eisenmenger syndrome is the most severe and extreme phenotype of pulmonary arterial
hypertension associated with congenital heart disease. A large nonrestrictive systemic left-to …

Background: Eisenmenger syndrome is associated with substantial morbidity and mortality.
There is no consensus, however, on mortality risk stratification. We aimed to investigate …

Objectives Despite advances in treatment of idiopathic pulmonary arterial hypertension
(IPAH), there remains no medical cure, and patients can experience disease progression …

Background Adults presenting with an unrepaired atrial septal defect and pulmonary arterial
hypertension (ASD-PAH) are typically classified as “correctable” or “non-correctable”. The …

Advances in cardiology and cardiac surgery have transformed the outlook for patients with
congenital heart disease (CHD) so that currently 85% of neonates with CHD survive into …

Background The relationship between pulmonary arterial hypertension-specific drug therapy
(PAH-SDT) and mortality in Eisenmenger syndrome (ES) is controversial. Aims To …

Pulmonary arterial hypertension (PAH) is an uncommon but serious disease characterized
by severe pulmonary vascular disease and significant morbidity and mortality. PAH …

Aims Survival in pulmonary arterial hypertension (PAH) and Eisenmenger syndrome (ES)
relates to right ventricular (RV) function. Little is known about differences of ventricular …

Objectives Approximately 5%–10% of adults with congenital heart disease (CHD) develop
pulmonary arterial hypertension (PAH), which affects life expectancy and quality of life …