Cisplatin is commonly used in combination with other cytotoxic agents as a standard
treatment regimen for a variety of solid tumors, such as lung, ovarian, testicular, and head …

The 21st century has shown us how rapidly the pandemic can evolve and devastate the life
of human beings without differentiating between the continents. Even after the global …

Background MicroRNAs (miRNAs) are promising therapeutic agents for non-alcoholic fatty
liver disease (NAFLD). This study aimed to identify key genes/proteins involved in NAFLD …

Low-grade inflammation and pathological endochondral ossification are key processes
underlying the progression of osteoarthritis, the most prevalent joint disease worldwide. In …

Colorectal cancer (CRC) is the most commonly diagnosed fatal cancer in both women and
men worldwide. CRC ranked second in mortality and third in incidence in 2020. It is difficult …

The pharmaceutical industry suffered a significant decline of innovation in the last few
decades, whose simple reason is complex biology. Artificial intelligence (AI) promises to …

Different types of DNA lesions forming in close vicinity, create clusters of damaged sites
termed as “clustered/complex DNA damage” and they are considered to be a major …

The rationale of the drug design method is generally focused on the designing of “magic
bullets” that acts on individual drug targets. This idea of “one gene, one target, one disease” …

Abstract Systems biology is concerned with the analysis and modelling of complex
biological systems using computational and mathematical tools. This deals with the …

Abstract System biology studies the large-scale measurement of biomolecules in intricate
biological systems. High-throughput omics, such as proteomics, transcriptomics, and …