Glucose metabolism in normal aging and Alzheimer's disease: methodological and physiological considerations for PET studies

L Mosconi - Clinical and translational imaging, 2013 - Springer
Alzheimer's disease (AD) is an age-dependent neurodegenerative disorder associated with
progressive loss of cognitive function. 2-[18 F] fluoro-2-deoxy-d-glucose (FDG) positron …

Advanced magnetic resonance spectroscopic neuroimaging: Experts' consensus recommendations

AA Maudsley, OC Andronesi, PB Barker… - NMR in …, 2021 - Wiley Online Library
Magnetic resonance spectroscopic imaging (MRSI) offers considerable promise for
monitoring metabolic alterations associated with disease or injury; however, to date, these …

EANM procedure guidelines for brain PET imaging using [18F]FDG, version 3

E Guedj, A Varrone, R Boellaard, NL Albert… - European journal of …, 2022 - Springer
The present procedural guidelines summarize the current views of the EANM Neuro-
Imaging Committee (NIC). The purpose of these guidelines is to assist nuclear medicine …

Metformin in amnestic mild cognitive impairment: results of a pilot randomized placebo controlled clinical trial

JA Luchsinger, T Perez, H Chang… - Journal of …, 2016 - content.iospress.com
Diabetes and hyperinsulinemia may be risk factors for Alzheimer's disease (AD). We
conducted a pilot study of metformin, a medication efficacious in treating and preventing …

The logopenic/phonological variant of primary progressive aphasia

ML Gorno-Tempini, SM Brambati, V Ginex, J Ogar… - Neurology, 2008 - AAN Enterprises
Objective: Primary progressive aphasia (PPA) is characterized by isolated decline in
language functions. Semantic dementia and progressive nonfluent aphasia are accepted …

A Standardized [18F]-FDG-PET Template for Spatial Normalization in Statistical Parametric Mapping of Dementia

PA Della Rosa, C Cerami, F Gallivanone, A Prestia… - Neuroinformatics, 2014 - Springer
Abstract [18 F]-fluorodeoxyglucose (FDG) Positron Emission Tomography (PET) is a widely
used diagnostic tool that can detect and quantify pathophysiology, as assessed through …

Discrimination between Alzheimer dementia and controls by automated analysis of multicenter FDG PET

K Herholz, E Salmon, D Perani, JC Baron, V Holthoff… - Neuroimage, 2002 - Elsevier
A new diagnostic indicator of FDG PET scan abnormality, based on age-adjusted t statistics
and an automated voxel-based procedure, is presented and validated in a large data set …

Cerebral metabolic changes accompanying conversion of mild cognitive impairment into Alzheimer's disease: a PET follow-up study

A Drzezga, N Lautenschlager, H Siebner… - European journal of …, 2003 - Springer
A high percentage of patients with mild cognitive impairment (MCI) develop clinical
dementia of the Alzheimer type (AD) within 1 year. The aim of this longitudinal study was to …

FDG PET in the differential diagnosis of parkinsonian disorders

T Eckert, A Barnes, V Dhawan, S Frucht, MF Gordon… - Neuroimage, 2005 - Elsevier
The differential diagnosis of parkinsonian disorders can be challenging, especially early in
the disease course. PET imaging with [18F]-fluorodeoxyglucose (FDG) has been used to …

[HTML][HTML] Validation of an optimized SPM procedure for FDG-PET in dementia diagnosis in a clinical setting

D Perani, PA Della Rosa, C Cerami, F Gallivanone… - NeuroImage: Clinical, 2014 - Elsevier
Diagnostic accuracy in FDG-PET imaging highly depends on the operating procedures. In
this clinical study on dementia, we compared the diagnostic accuracy at a single-subject …