Background & Aims We conducted a systematic review with meta-analysis to estimate rates
and trends of colectomy in patients with ulcerative colitis (UC), and of primary and re …

The management of Crohn's disease involves immunosuppressive protocols in a step-up
approach that progresses through a therapeutic pyramid with several tiers of medication …

Objectives: Temporal changes for intestinal resections for Crohn's disease (CD) are
controversial. We validated administrative database codes for CD diagnosis and surgery in …

Background Therapeutic management of inflammatory bowel diseases (IBD) is rapidly
evolving, with an expanding armoury of biological drugs at our disposal. However, real …

Objective Thiopurines are widely used as maintenance therapy in inflammatory bowel
disease (IBD) but the evidence base for their use is sparse and their role increasingly …

OBJECTIVES: The thiopurine (TP) analogs azathioprine and mercaptopurine have proven
efficacy in inducing and maintaining clinical remission in Crohn's disease (CD). Their impact …

Objective Severe endoscopic lesions (SEL) in patients with colonic Crohn's disease (CD)
have been linked to higher risk of colectomy. The aims of this study were to reassess the …

Abstract Background Many Crohn's disease (CD) patients will undergo surgery over the
course of their life. It is thought that with the introduction of disease-modifying agents like anti …

Abstract Background and Aims: In the past decades, treatment options and strategies for
ulcerative colitis [UC] have radically changed. Whether these developments have altered the …

Background It is unclear whether adherence to prescribing standards has been achieved in
inflammatory bowel disease (IBD). Aim To determine how prescribing of 5‐aminosalicylates …