Dose selection for phase III clinical evaluation of gepotidacin (GSK2140944) in the treatment of uncomplicated urinary tract infections

NE Scangarella-Oman, M Hossain… - Antimicrobial Agents …, 2022 - Am Soc Microbiol
Antibiotics are the current standard-of-care treatment for uncomplicated urinary tract
infections (uUTIs). However, increasing rates of bacterial antibiotic resistance necessitate …

[HTML][HTML] Psychosocial burden of recurrent uncomplicated urinary tract infections

KG Naber, J Tirán-Saucedo… - GMS Infectious …, 2022 - ncbi.nlm.nih.gov
Introduction: Urinary tract infections (UTI) are a leading cause of bacterial infections in
women. Despite acute treatment, 30–50% of women who have a UTI will experience a …

The emotional impact of urinary tract infections in women: a qualitative analysis

L Grigoryan, A Mulgirigama, M Powell… - BMC Women's …, 2022 - Springer
Background While many studies address the clinical management of participants with
uncomplicated urinary tract infection (uUTI), the emotional impact of uUTIs has been …

A reference standard for urinary tract infection research: a multidisciplinary Delphi consensus study

MP Bilsen, SP Conroy, C Schneeberger… - The Lancet Infectious …, 2024 - thelancet.com
The absence of a consensus-based reference standard for urinary tract infection (UTI)
research adversely affects the internal and external validity of diagnostic and therapeutic …

Qualitative analysis of a Twitter-disseminated survey reveals new patient perspectives on the impact of urinary tract infection

M Valentine-King, L Laytner, C Hines-Munson… - Antibiotics, 2022 - mdpi.com
Few studies have harnessed social media to explore patients' experiences with urinary tract
infection (UTI); therefore, we captured UTI experiences and future research suggestions …

Relationship between frailty and lower urinary tract symptoms among community‐dwelling adults

O Soma, S Hatakeyama, A Imai… - LUTS: Lower Urinary …, 2020 - Wiley Online Library
Objectives To evaluate the relationship between frailty and lower urinary tract symptoms
(LUTS), the association of frailty and LUTS remains unclear. Methods This cross‐sectional …

Allicin suppressed Escherichia coli-induced urinary tract infections by a novel MALT1/NF-κB pathway

Z Chang, L An, Z He, Y Zhang, S Li, M Lei, P Xu… - Food & Function, 2022 - pubs.rsc.org
Escherichia coli (E. coli) strains cause the majority of urinary tract infections (UTIs) and are
resistant to various antibiotics. Therefore, it is imperative to explore novel host-target …

Intravesical aminoglycoside instillations as prophylaxis for recurrent urinary tract infection: patient satisfaction, long-term safety and efficacy

MP Bilsen, JIM van Uhm, JE Stalenhoef… - JAC-Antimicrobial …, 2023 - academic.oup.com
Background Recurrent urinary tract infections (UTIs) are common, especially in women.
When oral antimicrobial prophylaxis is ineffective or not possible due to allergies or …

Predicting antibiotic susceptibility among patients with recurrent urinary tract infection using a prior culture

MA Valentine-King, BW Trautner, RJ Zoorob… - Journal of …, 2023 - journals.lww.com
Purpose: Recurrent cystitis guidelines recommend relying on a local antibiogram or prior
urine culture to guide empirical prescribing, yet little data exist to quantify the predictive …

Psychosocial impact of recurrent urogenital infections: a review

K Thomas-White, P Navarro, F Wever, L King… - Women's …, 2023 - journals.sagepub.com
Recurrent urogenital infections such as bacterial vaginosis, vulvovaginal candidiasis, and
urinary tract infections have a high prevalence and pronounced psychosocial impact …