miRNAs and long noncoding RNAs as biomarkers in human diseases

K Van Roosbroeck, J Pollet… - Expert review of molecular …, 2013 - Taylor & Francis
Noncoding RNAs (ncRNAs) are transcripts that have no apparent protein-coding capacity;
however, many ncRNAs have been found to play a major biological role in human …

Noncoding RNA: current deep sequencing data analysis approaches and challenges

D Veneziano, S Di Bella, G Nigita, A Lagana… - Human …, 2016 - Wiley Online Library
One of the most significant biological discoveries of the last decade is represented by the
reality that the vast majority of the transcribed genomic output comprises diverse classes of …

The involvement of microRNAs in major depression, suicidal behavior, and related disorders: a focus on miR-185 and miR-491-3p

G Serafini, M Pompili, KF Hansen, K Obrietan… - Cellular and molecular …, 2014 - Springer
Major depressive disorders are common and disabling conditions associated with significant
psychosocial impairment and suicide risk. At least 3–4% of all depressive individuals die by …

[HTML][HTML] Long noncoding RNA FOXD3-AS1 regulates oxidative stress-induced apoptosis via sponging microRNA-150

D Zhang, H Lee, JA Haspel, Y Jin - The FASEB Journal, 2017 - ncbi.nlm.nih.gov
The function of most human long noncoding RNAs (lncRNAs) remains unclear. Our studies
identified a highly up-regulated mammalian lncRNA, FOXD3-AS1, known as linc1623 in …

Computational approaches for the analysis of ncRNA through deep sequencing techniques

D Veneziano, G Nigita, A Ferro - Frontiers in bioengineering and …, 2015 - frontiersin.org
The majority of the human transcriptome is defined as non-coding RNA (ncRNA), since only
a small fraction of human DNA encodes for proteins, as reported by the ENCODE project …

MicroRNA‐mediated regulation of p21 and TASK1 cellular restriction factors enhances HIV‐1 infection

L Farberov, E Herzig, S Modai, O Isakov… - Journal of cell …, 2015 - journals.biologists.com
MicroRNAs (miRNAs) are short non‐coding RNAs that play a central role in the regulation of
gene expression by binding to target mRNAs. Several studies have revealed alterations in …

iMir: an integrated pipeline for high-throughput analysis of small non-coding RNA data obtained by smallRNA-Seq

G Giurato, MR De Filippo, A Rinaldi, A Hashim… - BMC …, 2013 - Springer
Background Qualitative and quantitative analysis of small non-coding RNAs by next
generation sequencing (smallRNA-Seq) represents a novel technology increasingly used to …

lncRNA FOXD3‐AS1 is associated with clinical progression and regulates cell migration and invasion in breast cancer

Y Guan, A Bhandari, E Xia, F Yang… - Cell biochemistry …, 2019 - Wiley Online Library
For women, breast cancer is the most commonly diagnosed cancer and the leading cause of
women deaths due to cancer. In recent years, increasing long noncoding RNA (lncRNA) has …

HIV-1 infection increases microRNAs that inhibit Dicer1, HRB and HIV-EP2, thereby reducing viral replication

S Modai, L Farberov, E Herzig, O Isakov, A Hizi… - PloS one, 2019 - journals.plos.org
HIV-1 is the causative agent of AIDS (Autoimmune Deficiency Syndrome). HIV-1 infection
results in systemic CD4+ T cell depletion, thereby impairing cell-mediated immunity …

Species‐specific micro RNA regulation influences phenotypic variability: Perspectives on species‐specific microRNA regulation

E Mor, N Shomron - Bioessays, 2013 - Wiley Online Library
Phenotypic divergence among animal species may be due in part to species‐specific (SS)
regulation of gene expression by small, non‐coding regulatory RNAs termed “microRNAs” …