One of the most significant biological discoveries of the last decade is represented by the reality that the vast majority of the transcribed genomic output comprises diverse classes of …
G Serafini, M Pompili, KF Hansen, K Obrietan… - Cellular and molecular …, 2014 - Springer
Major depressive disorders are common and disabling conditions associated with significant psychosocial impairment and suicide risk. At least 3–4% of all depressive individuals die by …
D Zhang, H Lee, JA Haspel, Y Jin - The FASEB Journal, 2017 - ncbi.nlm.nih.gov
The function of most human long noncoding RNAs (lncRNAs) remains unclear. Our studies identified a highly up-regulated mammalian lncRNA, FOXD3-AS1, known as linc1623 in …
D Veneziano, G Nigita, A Ferro - Frontiers in bioengineering and …, 2015 - frontiersin.org
The majority of the human transcriptome is defined as non-coding RNA (ncRNA), since only a small fraction of human DNA encodes for proteins, as reported by the ENCODE project …
L Farberov, E Herzig, S Modai, O Isakov… - Journal of cell …, 2015 - journals.biologists.com
MicroRNAs (miRNAs) are short non‐coding RNAs that play a central role in the regulation of gene expression by binding to target mRNAs. Several studies have revealed alterations in …
G Giurato, MR De Filippo, A Rinaldi, A Hashim… - BMC …, 2013 - Springer
Background Qualitative and quantitative analysis of small non-coding RNAs by next generation sequencing (smallRNA-Seq) represents a novel technology increasingly used to …
Y Guan, A Bhandari, E Xia, F Yang… - Cell biochemistry …, 2019 - Wiley Online Library
For women, breast cancer is the most commonly diagnosed cancer and the leading cause of women deaths due to cancer. In recent years, increasing long noncoding RNA (lncRNA) has …
S Modai, L Farberov, E Herzig, O Isakov, A Hizi… - PloS one, 2019 - journals.plos.org
HIV-1 is the causative agent of AIDS (Autoimmune Deficiency Syndrome). HIV-1 infection results in systemic CD4+ T cell depletion, thereby impairing cell-mediated immunity …
E Mor, N Shomron - Bioessays, 2013 - Wiley Online Library
Phenotypic divergence among animal species may be due in part to species‐specific (SS) regulation of gene expression by small, non‐coding regulatory RNAs termed “microRNAs” …