Protein data bank: a comprehensive review of 3D structure holdings and worldwide utilization by researchers, educators, and students

SK Burley, HM Berman, JM Duarte, Z Feng, JW Flatt… - Biomolecules, 2022 - mdpi.com
The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB),
funded by the United States National Science Foundation, National Institutes of Health, and …

RCSB Protein Data Bank (RCSB. org): delivery of experimentally-determined PDB structures alongside one million computed structure models of proteins from …

SK Burley, C Bhikadiya, C Bi, S Bittrich… - Nucleic acids …, 2023 - academic.oup.com
Abstract The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB
PDB), founding member of the Worldwide Protein Data Bank (wwPDB), is the US data center …

Critical assessment of methods of protein structure prediction (CASP)—Round XIV

A Kryshtafovych, T Schwede, M Topf… - Proteins: Structure …, 2021 - Wiley Online Library
Critical assessment of structure prediction (CASP) is a community experiment to advance
methods of computing three‐dimensional protein structure from amino acid sequence. Core …

[HTML][HTML] The accuracy of protein structures in solution determined by AlphaFold and NMR

NJ Fowler, MP Williamson - Structure, 2022 - cell.com
Summary In the recent Critical Assessment of Structure Prediction (CASP) competition,
AlphaFold2 performed outstandingly. Its worst predictions were for nuclear magnetic …

Predicting protein flexibility with AlphaFold

P Ma, DW Li, R Brüschweiler - Proteins: Structure, Function, and …, 2023 - Wiley Online Library
AlphaFold2 has revolutionized protein structure prediction from amino‐acid sequence. In
addition to protein structures, high‐resolution dynamics information about various protein …

Structural basis of bacteriophage T5 infection trigger and E. coli cell wall perforation

R Linares, CA Arnaud, G Effantin, C Darnault… - Science …, 2023 - science.org
Most bacteriophages present a tail allowing host recognition, cell wall perforation, and viral
DNA channeling from the capsid to the infected bacterium cytoplasm. The majority of tailed …

Protein target highlights in CASP15: Analysis of models by structure providers

LT Alexander, J Durairaj… - Proteins: Structure …, 2023 - Wiley Online Library
We present an in‐depth analysis of selected CASP15 targets, focusing on their biological
and functional significance. The authors of the structures identify and discuss key protein …

More than just pattern recognition: Prediction of uncommon protein structure features by AI methods

O Herzberg, J Moult - … of the National Academy of Sciences, 2023 - National Acad Sciences
The CASP14 experiment demonstrated the extraordinary structure modeling capabilities of
artificial intelligence (AI) methods. That result has ignited a fierce debate about what these …

Deciphering bacteriophage T5 host recognition mechanism and infection trigger

S Degroux, G Effantin, R Linares, G Schoehn… - Journal of …, 2023 - Am Soc Microbiol
Bacteriophages, viruses infecting bacteria, recognize their host with high specificity, binding
to either saccharide motifs or proteins of the cell wall of their host. In the majority of …

RNA target highlights in CASP15: Evaluation of predicted models by structure providers

RC Kretsch, ES Andersen, JM Bujnicki… - Proteins: Structure …, 2023 - Wiley Online Library
The first RNA category of the Critical Assessment of Techniques for Structure Prediction
competition was only made possible because of the scientists who provided experimental …