Despite a continuing debate about the existence of cancer stem cells (CSCs), recent
discoveries have provided further support for their existence and their roles in drug …

Inhibitors of DNA binding and cell differentiation (Id) proteins are members of the large
family of the helix-loop-helix (HLH) transcription factors, but they lack any DNA-binding motif …

The accessibility and transparency of the cornea permit robust stem cell labeling and in vivo
cell fate mapping. Limbal epithelial stem cells (LSCs) that renew the cornea are traditionally …

Breast cancer cells frequently home to the bone marrow, where they may enter a dormant
state before forming a bone metastasis. Several members of the interleukin-6 (IL-6) cytokine …

In this study, we investigated the role of cancer-associated fibroblasts (CAFs) in
hepatocellular carcinoma (HCC) progression. We showed that CAFs secrete high levels of …

Here, I propose that cancer stem cells (CSCs) would be equivalent to para-embryonic stem
cells (p-ESCs), derived from adult cells de-re-programmed to a ground state. p-ESCs would …

The ability for cells to harness alternative splicing enables them to diversify their proteome in
order to carry out complex biological functions and adapt to external and internal stimuli. The …

Abstract Background Cancer stem cells (CSCs) require stromal signals for maintaining
pluripotency and self-renewal capacities to confer tumor metastasis. Resolvin D1 (RvD1), an …

Resistance of chemotherapy is one of causes of recurrence and poor prognosis in patients
with colorectal cancer (CRC). The role of differentially expressed long non-coding RNA …

Alternative splicing (AS) is an important event that contributes to posttranscriptional gene
regulation. This process leads to several mature transcript variants with diverse …