To enhance weak sounds while compressing the dynamic intensity range, auditory sensory
cells amplify sound-induced vibrations in a nonlinear, intensity-dependent manner. In the …

Optical coherence tomography (OCT) has revolutionized physiological studies of the
hearing organ, the vibration and morphology of which can now be measured without …

Detection of low-level sounds by the mammalian cochlea requires electromechanical
feedback from outer hair cells (OHCs). This feedback arises due to the electromotile …

As a result of the cochlea's nonlinear mechanics, stimulation by two tones results in the
generation of distortion products (DPs) at frequencies flanking the primary tones. DPs are …

The middle ear transmits environmental sound to the inner ear. It also transmits acoustic
energy sourced within the inner ear out to the ear canal, where it can be detected with a …

It has been demonstrated that isolated auditory sensory cells, outer hair cells, can generate
distortion products at low frequencies. It remains unknown, however, whether or not motile …

Otoacoustic emissions, sounds generated by the inner ear, are widely used for diagnosing
hearing disorders and studying cochlear mechanics. However, it remains unclear how …

Outer hair cells (OHC) are key to the mammalian cochlear amplifier, powered by the lateral
membrane protein Prestin. In this study, we explored age-related OHC changes and how the …

Auditory frequency coding is place‐specific, which depends on the mechanical coupling of
the basilar membrane‐outer hair cell (OHC)‐tectorial membrane network. Prestin‐based …

The frequency selectivity of the mammalian auditory system is critical for discriminating
complex sounds like speech. This selectivity derives from the sharp tuning of the cochlea's …