Recently, there has been growing interest in genome sequencing, driven by advances in
sequencing technology, in terms of both efficiency and affordability. These developments …

About fifty times more data has been created than there are stars in the observable universe.
Current trends in data creation and consumption mean that the devices and storage media …

Sequencing data are rapidly accumulating in public repositories. Making this resource
accessible for interactive analysis at scale requires efficient approaches for its storage and …

We present Genozip, a universal and fully featured compression software for genomic data.
Genozip is designed to be a general-purpose software and a development framework for …

In recent years, the focus of bioinformatics research has moved from individual sequences to
collections of sequences. Given the fundamental role of the Burrows-Wheeler Transform …

The amount of data produced by modern sequencing instruments that needs to be stored is
huge. Therefore it is not surprising that a lot of work has been done in the field of specialized …

The cost of maintaining exabytes of data produced by sequencing experiments every year
has become a major issue in today's genomic research. In spite of the increasing popularity …

Background Nearly all molecular sequence databases currently use gzip for data
compression. Ongoing rapid accumulation of stored data calls for a more efficient …

With the increasing throughput of modern sequencing instruments, the cost of storing and
transmitting sequencing data has also increased dramatically. Although many tools have …

The development and progress of high-throughput sequencing technologies have
transformed the sequencing of DNA from a scientific research challenge to practice. With the …