Immune evasion strategies of pathogens in macrophages: the potential for limiting pathogen transmission

Y Ren, FA Khan, NS Pandupuspitasari… - Current issues in …, 2017 - mdpi.com
Preventing pathogen transmission to a new host is of major interest to the immunologist and
could benefit from a detailed investigation of pathogen immune evasion strategies. The first …

The role of Bax in the apoptosis of Leishmania-infected macrophages

M Aghaei, H KhanAhmad, S Aghaei… - Microbial …, 2020 - Elsevier
Background Leishmania is a protozoan parasite that nests in macrophages and is
responsible for the Leishmaniasis disease. In spite of different defense pathways, last …

Inhibitory effects of a water-soluble jujube polysaccharide against biofilm-forming oral pathogenic bacteria

D Xu, J Xiao, D Jiang, Y Liu, Z Gou, J Li, M Shi… - International Journal of …, 2022 - Elsevier
Oral diseases caused by infectious pathogens raises significant concerns in public health. In
the light of side effects of current antibiotics therapy and growing drug resistance of …

Activation of TNFR2 sensitizes macrophages for TNFR1-mediated necroptosis

D Siegmund, J Kums, M Ehrenschwender… - Cell death & …, 2016 - nature.com
Macrophages express TNFR1 as well as TNFR2 and are also major producers of tumor
necrosis factor (TNF), especially upon contact with pathogen-associated molecular patterns …

Linoleic acid metabolism activation in macrophages promotes the clearing of intracellular Staphylococcus aureus

B Yan, K Fung, S Ye, PM Lai, YX Wei, KH Sze… - Chemical …, 2022 - pubs.rsc.org
Multidrug-resistant bacterial pathogens pose an increasing threat to human health. Certain
bacteria, such as Staphylococcus aureus, are able to survive within professional phagocytes …

Targeting macrophage polarization in infectious diseases: M1/M2 functional profiles, immune signaling and microbial virulence factors

CD Cerdeira, MRPL Brigagão - Immunological Investigations, 2024 - Taylor & Francis
Introduction: An event of increasing interest during host-pathogen interactions is the
polarization of patrolling/naive monocytes (MOs) into macrophage subsets (MФs) …

Novel peptide motifs from lysozyme suppress pro-inflammatory cytokines in macrophages by antagonizing toll-like receptor and LPS-scavenging action

HR Ibrahim, K Hamasaki, T Miyata - European Journal of Pharmaceutical …, 2017 - Elsevier
Lysozyme is commonly found in spots where bacterial infections are most likely to enter the
body. Earlier we found that lysozyme possesses five antimicrobial peptide motifs in its N …

TLR22-mediated activation of TNF-α-caspase-1/IL-1β inflammatory axis leads to apoptosis of Aeromonas hydrophila-infected macrophages

M Kumar, J Kumar, S Sharma, MA Hussain… - Molecular …, 2021 - Elsevier
Toll-like receptors (TLRs) represent first line of host defence against microbes. Amongst
different TLRs, TLR22 is exclusively expressed in non-mammalian vertebrates, including …

Modulation of human dendritic cell activity by Giardia and helminth antigens

A Summan, P Nejsum, AR Williams - Parasite Immunology, 2018 - Wiley Online Library
Giardia duodenalis is a common intestinal protozoan parasite known to modulate host
immune responses, including dendritic cell (DC) function. Coinfections of intestinal …

[HTML][HTML] Disentangling the immune response and host-pathogen interactions in Francisella noatunensis infected Atlantic cod

MH Solbakken, S Jentoft, T Reitan, H Mikkelsen… - … and Physiology Part D …, 2019 - Elsevier
The genetic repertoire underlying teleost immunity has been shown to be highly variable. A
rare example is Atlantic cod and its relatives Gadiformes that lacks a hallmark of vertebrate …