During osteogenesis, osteoblasts lay down osteoid and transform into osteocytes embedded
in mineralized bone matrix. Despite the fact that osteocytes are the most abundant cellular …

The development of skeletal disorders in larval and juvenile fish is linked to a poorly
understood relationship between nutrition, environment and genetic factors. These disorders …

Resorption and remodelling of skeletal tissues is required for development and growth,
mechanical adaptation, repair, and mineral homeostasis of the vertebrate skeleton. Here we …

The zebrafish is as an important vertebrate animal model system for studying developmental
processes, gene functions and signalling pathways. It is also used as a model system for the …

Developmental osteogenesis and pathologies of mineralized tissues are areas of intense
investigations in the mammalian field, but different from other areas of organ formation and …

The vertebrate skeleton is a plastic organ system and the skeleton of teleosts is no
exception. Epigenetic factors during development influence skeletal anatomy, mechanical …

The present review aims to systematically and critically analyze the current knowledge on
phospholipases and their role in physiological and pathological mineralization undertaken …

The bone material of almost all vertebrates contains the same cellular components. These
comprise osteoblasts that produce bone, osteoclasts that resorb bone and osteocytes, which …

Plasticity of skeletal cells, tissues and organs is a general vertebrate character and rampant
among teleost fishes. Plasticity is not restricted to early ontogeny but is evident throughout …

One of the main constrains for commercial aquaculture production of white seabream
(Diplodus sargus) is the high incidence of skeletal malformations in reared fish. The purpose …