Specific molecular recognition is assumed to require a well-defined set of contacts and devoid of conformational and interaction ambiguities. Growing experimental evidence …
R Koradi, M Billeter, K Wüthrich - Journal of molecular graphics, 1996 - Elsevier
MOLMOL is a molecular graphics program for display, analysis, and manipulation of three- dimensional structures of biological macromolecules, with special emphasis on nuclear …
CA Davey, DF Sargent, K Luger, AW Maeder… - Journal of molecular …, 2002 - Elsevier
Solvent binding in the nucleosome core particle containing a 147 base pair, defined- sequence DNA is characterized from the X-ray crystal structure at 1.9 Å resolution. A single …
The 3D solution structure of the GCC‐box binding domain of a protein from Arabidopsis thaliana in complex with its target DNA fragment has been determined by heteronuclear …
P Callaerts, G Halder, WJ Gehring - Annual review of …, 1997 - annualreviews.org
▪ Abstract Pax-6 is a member of the Pax gene class and encodes a protein containing a paired domain and a homeodomain. The molecular characterization of Pax-6 genes from …
R Joshi, JM Passner, R Rohs, R Jain, A Sosinsky… - Cell, 2007 - cell.com
The recognition of specific DNA-binding sites by transcription factors is a critical yet poorly understood step in the control of gene expression. Members of the Hox family of …
Macromolecular complex formation is governed by two opposing constraints of specificity and speed,. Kinetic,,, and theoretical considerations suggest that significant rate …
Telomeres, the nucleoprotein complexes at the ends of eukaryotic chromosomes, are essential for chromosome stability. In the yeast S. cerevisiae, telomeric DNA is bound in a …