Loneliness, or the subjective feeling of social isolation, is an important social determinant of
health. Loneliness is associated with poor physical health, including higher rates of …

Parental stress drastically impairs cognitive and behavioral functions of the offspring. Social
isolation, as one of the most stressful conditions for social animals including rats induces a …

Environmental enrichment (EE) through combination of social and non-biological stimuli
enhances activity-dependent synaptic plasticity and improves behavioural performance. Our …

Social isolation affects physical functioning owing to psychological stress. We constructed a
rat model to clarify the unexplored effects of social isolation and to determine whether …

Rearing environment plays a vital role in maintaining physical and mental health of both
animals and humans. Plenty of studies have proved that physical environment enrichment in …

Introduction: This study investigates the effects of social isolation on mental health and
cognitive functions in Sprague Dawley (SD) and Wistar Albino (WIS) rat strains, prompted by …

Background and aim Social isolation stress (SIS) is a stressor known to trigger depressive
behaviors. Psychiatric disorders are associated with neurobiological changes, such as …

Learning and memory are affected by novel enriched environment, a condition where
animals play and interact with a variety of toys and conspecifics. Exposure of animals to the …

Chronic neuropathic pain is often accompanied with comorbid anxiety. However, effective
interventions of this anxiety are highly limited. This study aims to examine the effect of …