Many clinically used drugs are derived from or inspired by bacterial natural products that
often are produced through nonribosomal peptide synthetases (NRPSs), megasynthetases …

Siderophore is a diverse family of secondary metabolites that exhibit high affinities for
binding and chelating iron, one of the essential elements for cellular processes, including …

Pseudodiploöspora longispora (previously known as Diploöspora longispora) is a
pathogenic fungus of Morchella mushrooms. The molecular mechanism underlying the …

Microbial secondary metabolites have long been recognized as a rich source for
pharmaceutical compound discovery and to have crucial ecological functions. However, the …

Corallorazines are cyclic lipodipeptide natural products produced by the myxobacterium
Corallococcus coralloides B035. To decipher the basis of corallorazine biosynthesis, the …

The modular architecture of nonribosomal peptide synthetases (NRPSs) has inspired efforts
to study their evolution and engineering. In this study, we analyze in detail a unique family of …

Predicting bacterial social interactions from genome sequences is notoriously hard. Here,
we developed bioinformatic tools to predict how siderophores—secreted iron-scavenging …

Iron is a critical yet limited nutrient for microbial growth. To scavenge iron, most microbes
produce siderophores—diverse small molecules with high iron affinities. Different …

Fusarium poae is of concern to plant pathologists as it is a globally distributed contributor to
Fusarium head blight in wheat, barley and oats, and threatens consumers by the production …