Animal models of nonalcoholic fatty liver disease—a starter's guide

MA Van Herck, L Vonghia, SM Francque - Nutrients, 2017 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) constitutes a major health concern with the
increasing incidence of obesity and diabetes in many Western countries, reaching a …

Nonalcoholic fatty liver disease: pathogenesis and disease spectrum

T Hardy, F Oakley, QM Anstee… - Annual review of …, 2016 - annualreviews.org
Nonalcoholic fatty liver disease (NAFLD) is the most common cause of liver dysfunction in
the Western world and is increasing owing to its close association with obesity and insulin …

[HTML][HTML] Animal models of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis

Y Takahashi, Y Soejima, T Fukusato - World journal of …, 2012 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) is a condition in which excess fat accumulates in
the liver of a patient without a history of alcohol abuse. Nonalcoholic steatohepatitis (NASH) …

[HTML][HTML] Animal models of NAFLD from a hepatologist's point of view

D Jahn, S Kircher, HM Hermanns, A Geier - Biochimica et Biophysica Acta …, 2019 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disorder closely linked to obesity,
hyperlipidemia and type 2 diabetes and is increasingly recognized as a major health …

The weight of leptin in immunity

AL Cava, G Matarese - Nature Reviews Immunology, 2004 - nature.com
Leptin is an adipocyte-derived hormone/cytokine that links nutritional status with
neuroendocrine and immune functions. As a hormone, leptin regulates food intake and …

[PDF][PDF] Insulin resistance: a metabolic pathway to chronic liver disease

E Bugianesi, AJ McCullough, G Marchesini - Hepatology, 2005 - Wiley Online Library
Insulin resistance (IR) is the pathophysiological hallmark of nonalcoholic fatty liver disease
(NAFLD), one of the most common causes of chronic liver disease in Western countries. We …

Circulating leptin in non-alcoholic fatty liver disease: a systematic review and meta-analysis

SA Polyzos, KN Aronis, J Kountouras, DD Raptis… - Diabetologia, 2016 - Springer
Aims/hypothesis Clinical data regarding circulating leptin levels in patients with non-
alcoholic fatty liver disease (NAFLD) are conflicting. The purpose of this meta-analysis was …

Metabolic spectrum of liver failure in type 2 diabetes and obesity: from NAFLD to NASH to HCC

H Kim, DS Lee, TH An, HJ Park, WK Kim… - International journal of …, 2021 - mdpi.com
Liver disease is the spectrum of liver damage ranging from simple steatosis called as
nonalcoholic fatty liver disease (NAFLD) to hepatocellular carcinoma (HCC). Clinically …

Mouse models in non‐alcoholic fatty liver disease and steatohepatitis research

QM Anstee, RD Goldin - International journal of experimental …, 2006 - Wiley Online Library
Non‐alcoholic fatty liver disease (NAFLD) represents a histological spectrum of liver disease
associated with obesity, diabetes and insulin resistance that extends from isolated steatosis …

Animal models of nonalcoholic steatohepatitis: eat, delete, and inflame

SH Ibrahim, P Hirsova, H Malhi, GJ Gores - Digestive diseases and …, 2016 - Springer
With the obesity epidemic, nonalcoholic fatty liver disease (NAFLD) has become a public
health problem with increasing prevalence. The mechanism of disease progression remains …