Hypertension is a global public health issue and the leading cause of premature death in
humans. Despite more than a century of research, hypertension remains difficult to cure due …

The development of high blood pressure is influenced by genetic and environmental factors,
with high salt intake being a known environmental contributor. Humans display a spectrum …

Salt-sensitivity of blood pressure is an independent risk factor for cardiovascular disease
and affects approximately half of the hypertensive population. While the precise …

The prevalence of kidney diseases has been increasing worldwide due to the aging
population and has results in an increased socioeconomic burden as well as increased …

Dietary potassium (K+) supplementation is associated with a lowering effect in blood
pressure (BP), but not all studies agree. Here, we examined the effects of short-and long …

Epithelial sodium channels (ENaC) are part of a complex network of interacting biochemical
pathways and as such are involved in several disease states. Dependent on site and type of …

The epithelial sodium channel (ENaC) is a heterotrimer and is widely distributed throughout
the kidneys, blood vessels, lungs, colons, and many other organs. The basic role of the …

According to the correlation of saltiness determined by electronic tongue and perceived
NaCl concentration, favorable enzymatic hydrolysis parameters were achieved to prepare …

The progression of diabetic kidney disease (DKD), a leading cause of end-stage kidney
disease, involves mineralocorticoid receptor (MR) activation. We previously identified …

It has recently been shown that taste receptors, in addition to being present in the oral cavity,
exist in various extra-oral organs and tissues such as the thyroid, lungs, skin, stomach …