Kidney involvement in patients with coronavirus disease 2019 (COVID-19) is common, and
can range from the presence of proteinuria and haematuria to acute kidney injury (AKI) …

Acute kidney injury (AKI) is now recognized as a heterogeneous syndrome that not only
affects acute morbidity and mortality, but also a patient's long-term prognosis. In this …

Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to
infection (1). Sepsis and septic shock are major healthcare problems, impacting millions of …

Background Whether the use of balanced multielectrolyte solution (BMES) in preference to
0.9% sodium chloride solution (saline) in critically ill patients reduces the risk of acute kidney …

Surviving Sepsis Campaign: International... : Critical Care Medicine Executive Summary:
Surviving Sepsis Campaign: International Guidelines for the Management of Sepsis and Septic …

Background: Sepsis/septic shock is a life-threatening and time-dependent condition that
requires timely management to reduce mortality. This review aims to update physicians with …

Bloodstream infection (BSI) is defined by positive blood cultures in a patient with systemic
signs of infection and may be either secondary to a documented source or primary—that is …

Purpose Sepsis is a heterogeneous syndrome and identification of sub-phenotypes is
essential. This study used trajectories of vital signs to develop and validate sub-phenotypes …

Importance Saline (0.9% sodium chloride), the fluid most commonly used to treat diabetic
ketoacidosis (DKA), can cause hyperchloremic metabolic acidosis. Balanced crystalloids, an …

Importance Approximately 20% to 30% of patients admitted to an intensive care unit have
sepsis. While fluid therapy typically begins in the emergency department, intravenous fluids …