Advanced targeted therapies in cancer: Drug nanocarriers, the future of chemotherapy

E Pérez-Herrero, A Fernández-Medarde - European journal of …, 2015 - Elsevier
Cancer is the second worldwide cause of death, exceeded only by cardiovascular diseases.
It is characterized by uncontrolled cell proliferation and an absence of cell death that, except …

Design of polymeric nanoparticles for biomedical delivery applications

M Elsabahy, KL Wooley - Chemical Society Reviews, 2012 - pubs.rsc.org
Polymeric nanoparticles-based therapeutics show great promise in the treatment of a wide
range of diseases, due to the flexibility in which their structures can be modified, with …

Nanomedicine (s) under the microscope

R Duncan, R Gaspar - Molecular pharmaceutics, 2011 - ACS Publications
Depending on the context, nanotechnologies developed as nanomedicines (nanosized
therapeutics and imaging agents) are presented as either a remarkable technological …

Polymeric conjugates for drug delivery

N Larson, H Ghandehari - Chemistry of Materials, 2012 - ACS Publications
The field of polymer therapeutics has evolved over the past decade and has resulted in the
development of polymer–drug conjugates with a wide variety of architectures and chemical …

The effects of polymeric nanostructure shape on drug delivery

S Venkataraman, JL Hedrick, ZY Ong, C Yang… - Advanced drug delivery …, 2011 - Elsevier
Amphiphilic polymeric nanostructures have long been well-recognized as an excellent
candidate for drug delivery applications. With the recent advances in the “top-down” and …

Design of biocompatible dendrimers for cancer diagnosis and therapy: current status and future perspectives

Y Cheng, L Zhao, Y Li, T Xu - Chemical Society Reviews, 2011 - pubs.rsc.org
In the past decade, nanomedicine with its promise of improved therapy and diagnostics has
revolutionized conventional health care and medical technology. Dendrimers and dendrimer …

Self-cross-linked polymer nanogels: a versatile nanoscopic drug delivery platform

JH Ryu, RT Chacko, S Jiwpanich… - Journal of the …, 2010 - ACS Publications
Nanoscopic vehicles that stably encapsulate drug molecules and release them in response
to a specific trigger are of great interest due to implications in therapeutic applications …

Biodegradable dendrimers for drug delivery

D Huang, D Wu - Materials Science and Engineering: C, 2018 - Elsevier
Dendrimers, as a type of artificial polymers with unique structural features, have been
extensively explored for their applications in biomedical fields, especially in drug delivery …

Advances in the chemistry of dendrimers

M Sowinska, Z Urbanczyk-Lipkowska - New Journal of Chemistry, 2014 - pubs.rsc.org
Dendrimers, which are highly branched, multivalent and monodisperse polymers, have
received continuous interest in recent years because of the global demand for new …

Glutathione-triggered “off–on” release of anticancer drugs from dendrimer-encapsulated gold nanoparticles

X Wang, X Cai, J Hu, N Shao, F Wang… - Journal of the …, 2013 - ACS Publications
Polymeric nanoparticles that can stably load anticancer drugs and release them in response
to a specific trigger such as glutathione are of great interest in cancer therapy. In the present …